Evidence map›Paper›PMID 35086944›Full record

Trial reportBMJ open diabetes research & care2022

Amount and intensity effects of exercise training alone versus a combined diet and exercise lifestyle intervention on health-related quality of life in the STRRIDE-PD randomized trial.

Katherine A Collins, Leanna M Ross, Lucy W Piner, Liezl B Fos, Cris A Slentz, Lori A Bateman, Leslie H Willis, Connie W Bales, Ilene C Siegler, Ruth Q Wolever and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open diabetes research & care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Katherine A CollinsDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA katherine.collins791@duke.edu.ORCID 0000-0001-9712-8980
Leanna M RossDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-1407-1622
Lucy W PinerEmeritis, Duke University School of Medicine, Durham, North Carolina, USA.
Liezl B FosDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Cris A SlentzEmeritis, Duke University School of Medicine, Durham, North Carolina, USA.
Lori A BatemanDepartment of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Leslie H WillisDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Connie W BalesDepartment of Geriatrics, Duke University School of Medicine, Durham, North Carolina, USA.
Ilene C SieglerDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Ruth Q WoleverDepartment of Physical Medicine and Rehabilitation, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Kim M HuffmanDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.
William E KrausDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0003-1930-9684
Duke University · USUniversity of North Carolina at Chapel Hill · USVanderbilt University · US

Funding

MULTIDISCIPLINARY HEART &VASCULAR DISEASEST32HL007101 · NHLBI · DUKE UNIVERSITY · PI FREEDMAN, NEIL J. · 1985 to 2020
$9.8M
Exercise Dose-Response Effects in Prediabetes:Responses and MechanismsR01DK081559 · NIDDK · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 2009 to 2013
$3.1M
Preparing Genetic Counselors for Genomic Medicine ResearchT32HG008955 · NHGRI · DUKE UNIVERSITY · PI COONEY, KATHLEEN A, HAGA, SUSANNE · 2017 to 2021
$2.0M
Enhanced Protein Intake During Obesity Reduction in Older Male Veterans: Differences in Physical Function and Muscle Quality Responses by RaceI01RX002843 · VA · DURHAM VA MEDICAL CENTER · PI BALES, CONNIE W · 2019 to 2023
–
NHGRI NIH HHS T32 HG008955NHLBI NIH HHS T32 HL007101NIDDK NIH HHS R01 DK081559RRD VA I01 RX002843
6 · The paper itself

Abstract

introductionTo determine the relative contributions of various amounts and intensities of exercise alone to a combined lifestyle intervention on health-related quality of life (HrQoL) measures. RESEARCH DESIGN AND

methodsParticipants (n=162) were sedentary, overweight/obese, with pre-diabetes, and randomized to one of four 6-month interventions: (1) high amount/moderate intensity exercise-energy expenditure of 16 kcal/kg of body weight/week (KKW) at 50% oxygen consumption (V̇O

resultsAcross the intervention, all groups (p<0.05) improved the physical component, SPF, and SPA scores. Only the low/moderate/diet group (p<0.001) significantly improved the mental component score. The high/vigorous group achieved 84.5% of the low/moderate/diet group effect for change in physical component score, and the low/moderate group achieved 83.7% of the low/moderate/diet group effect for change in mental component score.

conclusionsIn general, a low amount of moderate intensity exercise combined with diet was the most effective intervention for improving HrQoL. Of the exercise-only interventions, vigorous intensity exercise provided the greatest impact on changes in physical function. On the other hand, low amounts of moderate intensity exercise provided the greatest impact on mental well-being, potentially being a more attainable exercise dose for previously sedentary individuals with pre-diabetes to achieve.

Indexed as

ExerciseQuality of LifeDietHumansLife StyleObesitycaloric restrictiondiabetes mellitusexercisequality of lifetype 2

Identifiers

PMID35086944
PMCPMC8796224
OpenAlexW4210422680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.