Evidence map›Paper›PMID 35086929›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Ecdysone exerts biphasic control of regenerative signaling, coordinating the completion of regeneration with developmental progression.

Faith Karanja, Subhshri Sahu, Sara Weintraub, Rajan Bhandari, Rebecca Jaszczak, Jason Sitt, Adrian Halme

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. E93 controls adult differentiation by repressingProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Frontiers in cell and developmental biology · 2024
    Review
  12. Inter-organ communication during tissue regeneration.Development (Cambridge, England) · 2023
    Review
  13. Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.Frontiers in cell and developmental biology · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Faith KaranjaDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902.
Subhshri SahuDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902.ORCID 0000-0003-4808-7515
Sara WeintraubDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902.
Rajan BhandariDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902.
Rebecca JaszczakDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902.ORCID 0000-0003-2588-8790
Jason SittDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902.
Adrian HalmeDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22902 ajh6a@virginia.edu.ORCID 0000-0002-6608-5305

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008715 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LAURIE, GORDON WILLIAM · 2000 to 2019
$6.6M
Dissection of a Developmental Checkpoint That Preserves Regenerative CapacityR01GM099803 · NIGMS · UNIVERSITY OF VIRGINIA · PI HALME, ADRIAN J · 2012 to 2016
$1.5M
NIGMS NIH HHS R01 GM099803NIGMS NIH HHS T32 GM008715
6 · The paper itself

Abstract

In

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsEcdysoneGene ExpressionGene Expression Regulation, DevelopmentalGonadal Steroid HormonesImaginal DiscsIntercellular Signaling Peptides and ProteinsLarvaNeuronsRegenerationSignal TransductionTranscription FactorsWings, AnimalWnt1 ProteinBr protein, DrosophilaDrosophila ProteinsEcdysoneGonadal Steroid Hormonesinsulin-like peptide 8, DrosophilaIntercellular Signaling Peptides and ProteinsTranscription Factorswg protein, DrosophilaWnt1 ProteinBroadDilp8ecdysoneregenerationwingless

Identifiers

PMID35086929
PMCPMC8812538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.