Evidence map›Paper›PMID 35086849›Full record

ArticleBMJ open gastroenterology2022

Racial disparities in transjugular intrahepatic portosystemic shunt procedure outcomes.

James H Helzberg, Alice Parish, Donna Niedzwiecki, Charles Y Kim, Yuval A Patel, Julius M Wilder, Andrew J Muir

Open access · goldAbstract read
In one paragraph

Article in BMJ open gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Racial Disparities in Upper Gastrointestinal Hemorrhage Treatment.Journal of racial and ethnic health disparities · 2026
    Article
  2. Article
  3. Article
  4. Health disparities in cirrhosis care and liver transplantation.Nature reviews. Gastroenterology & hepatology · 2025
    Review
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

James H HelzbergDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0003-3888-9661
Alice ParishDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.
Donna NiedzwieckiDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.
Charles Y KimDepartment of Radiology, Division of Interventional Radiology, Duke University School of Medicine, Durham, North Carolina, USA.
Yuval A PatelDepartment of Medicine, Division of Gastroenterology, Duke University School of Medicine, Durham, North Carolina, USA.
Julius M WilderDepartment of Medicine, Division of Gastroenterology, Duke University School of Medicine, Durham, North Carolina, USA.
Andrew J MuirDepartment of Medicine, Division of Gastroenterology, Duke University School of Medicine, Durham, North Carolina, USA Andrew.Muir@duke.edu.
Duke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe transjugular intrahepatic portosystemic shunt (TIPS) procedure is an important intervention for management of complications of portal hypertension. The objective of this study was to identify predictors of mortality from the TIPS procedure with a focus on race and ethnicity.

designTIPS procedures from 2012 to 2014 in the National Inpatient Sample were identified. Weighting was applied to generate nationally representative results. In-hospital mortality was the primary outcome of interest. χ

results17 175 (95% CI 16 254 to 18 096) TIPS cases were identified. Approximately 71% were non-Hispanic (NH) white, 6% were NH black, 16% were Hispanic and 7% were other. NH black patients undergoing TIPS had an in-hospital mortality rate of 20.1%, nearly double the in-hospital mortality of any other racial or ethnic group. NH black patients also had significantly longer median postprocedure and total lengths of stay (p=0.03 and p<0.001, respectively). The interaction of race by clinical indication was a significant predictor of in-hospital mortality (p<0.001). NH black patients had increased mortality compared with other racial/ethnic groups when presenting with bleeding oesophageal varices (OR 3.85, 95% CI 2.14 to 6.95).

conclusionThis cohort study presents important findings in end-stage liver disease care, with clear racial disparities in in-hospital outcomes following the TIPS procedure. Specifically, black patients had significantly higher in-hospital mortality and longer lengths of stay. Further research is needed to understand how we can better care for black patients with liver disease.

Indexed as

Esophageal and Gastric VaricesHypertension, PortalPortasystemic Shunt, Transjugular IntrahepaticCohort StudiesGastrointestinal HemorrhageHumanschronic liver diseasecirrhosisportal hypertension

Identifiers

PMID35086849
PMCPMC8796249
OpenAlexW4210805766

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.