Evidence map›Paper›PMID 35086486›Full record

ArticleBMC neurology2022

Impact of COVID-19 infection among myasthenia gravis patients- a Cerner Real-World Data

Lakshmi Prasanna Digala, Shivika Prasanna, Praveen Rao, Adnan I Qureshi, Raghav Govindarajan

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. The impacts of the COVID-19 pandemic on Australia's myasthenia gravis patients: A self-reported survey study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lakshmi Prasanna DigalaDepartment of Neurology, University of Missouri Health Care, Columbia, MO, 65201, USA. laxmi.racherla@gmail.com.
Shivika PrasannaCenter for Biomedical Informatics, Department of Electrical Engineering & Computer Science, University of Missouri, Columbia, MO, 65201, USA.
Praveen RaoCenter for Biomedical Informatics, Department of Electrical Engineering & Computer Science, University of Missouri, Columbia, MO, 65201, USA.
Adnan I QureshiDepartment of Neurology, University of Missouri Health Care, Columbia, MO, 65201, USA.
Raghav GovindarajanDepartment of Neurology, University of Missouri Health Care, Columbia, MO, 65201, USA.
University of Missouri · USCentraCare Health System · USUniversity of Missouri Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyasthenia gravis (MG) is an auto-immune disease, and the mainstay of therapy is immunomodulation. Such patients are at high risk of acquiring any infections. Hence, we sought to determine the impact of the current global pandemic COVID-19 infection in MG patients.

methodsFor our study, we used Cerner Real-World Data

resultsIn the COVID-19 data set, a total of twenty-seven myasthenia patients were identified with a positive COVID-19 infection, and four were diagnosed with an exacerbation. The male to female ratio was equal and one unknown gender (3.7%) with a mean (± SD) age of 64.33 ± 18.42 years. This study group was compared with a non-COVID-19 data set in which a total of sixty-four myasthenia patients were identified, and twenty-three had an exacerbation. Among the 13 hospitalized patients in the two groups, the mean length of hospitalization for the myasthenia patients in the COVID-19 data set was 8.28 days (n = 7), and the non-COVID-19 set was 4.33 days (n = 6), and it was statistically significant (p-value= 0.007).

conclusionsThe mean length of hospital stay is prolonged in myasthenia patients who tested positive for COVID-19.

Indexed as

COVID-19Myasthenia GravisAgedAged, 80 and overData CollectionFemaleHumansMaleMiddle AgedPandemicsSARS-CoV-2

Identifiers

PMID35086486
PMCPMC8792518
OpenAlexW4226438903

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.