Evidence map›Paper›PMID 35086369›Full record

ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2023

Prefrontal Cortical Control of Anxiety: Recent Advances.

Nancy R Mack, Suixin Deng, Sha-Sha Yang, Yousheng Shu, Wen-Jun Gao

Open access · greenAbstract readReview
In one paragraph

Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nancy R MackDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA.
Suixin DengState Key Laboratory of Medical Neurobiology, Institute for Translational Brain Research, MOE Frontiers Center for Brain Science, Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Sha-Sha YangDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA.
Yousheng ShuState Key Laboratory of Medical Neurobiology, Institute for Translational Brain Research, MOE Frontiers Center for Brain Science, Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-2834-2876
Wen-Jun GaoDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA.
Drexel University · USFudan University · CN

Funding

Development of NMDAR hypofunction and cognitive deficitsR01MH085666 · NIMH · DREXEL UNIVERSITY · PI GAO, WEN-JUN · 2009 to 2018
$3.8M
Corticothalamic control of social motivationR01MH131053 · NIMH · DREXEL UNIVERSITY · PI Wen-Jun Gao · 2022 to 2026
$1.9M
Targeting parvalbumin neurons in the PFC for cognitive deficitsR21MH111609 · NIMH · DREXEL UNIVERSITY · PI GAO, WEN-JUN · 2017 to 2018
$430k
Role of prefrontal cortical dopamine in aggressionR21MH110678 · NIMH · DREXEL UNIVERSITY · PI GAO, WEN-JUN · 2016 to 2017
$425k
Behavioral effects of igsf9b in the prefrontal cortexR21MH121836 · NIMH · DREXEL UNIVERSITY · PI GAO, WEN-JUN · 2020 to 2020
$425k
Norepinephrine tunes prefrontal-thalamic circuitry to modulate avoidance behaviorR21MH129989 · NIMH · DREXEL UNIVERSITY · PI GAO, WEN-JUN · 2022 to 2023
$410k
Roles of NMDA receptors in schizophrenia pathological processR21MH079117 · NIMH · DREXEL UNIVERSITY · PI GAO, WEN-JUN · 2007 to 2008
$365k
NIMH NIH HHS R01 MH085666NIMH NIH HHS R01 MH131053NIMH NIH HHS R21 MH079117NIMH NIH HHS R21 MH110678NIMH NIH HHS R21 MH111609NIMH NIH HHS R21 MH121836NIMH NIH HHS R21 MH129989
6 · The paper itself

Abstract

Dysfunction in the prefrontal cortex is commonly implicated in anxiety disorders, but the mechanisms remain unclear. Approach-avoidance conflict tasks have been extensively used in animal research to better understand how changes in neural activity within the prefrontal cortex contribute to avoidance behaviors, which are believed to play a major role in the maintenance of anxiety disorders. In this article, we first review studies utilizing

Indexed as

AnxietyAnxiety DisordersAnimalsAvoidance LearningNeural PathwaysPrefrontal Cortexanxietyavoidanceinterneuronsoscillationsprefrontal cortexrodent

Identifiers

PMID35086369
PMCPMC9869286
OpenAlexW4210775675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.