Evidence map›Paper›PMID 35086254›Full record

ArticleIndian journal of ophthalmology2022

Orbital magnetic resonance imaging profile and clinicoradiological correlation in COVID-19-associated rhino-orbital-cerebral mucormycosis: A single-center study of 270 patients from North India.

Maya Hada, Parul Gupta, Meenu Bagarhatta, Koushik Tripathy, Anita Harsh, Kamlesh Khilnani, Kuldeep Mendiratta, Sunita Agarwal, Jugal Kishore Chouhan, Sudhir Bhandari

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Utility of intraoperative scoring system in rhino-orbital mucormycosis as a prognostic tool.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2024
    Article
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Maya HadaDepartment of Ophthalmology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Parul GuptaDepartment of Radiodiagnosis, SMS Medical College and Hospital, Jaipur, Rajasthan, India, India.
Meenu BagarhattaDepartment of Radiodiagnosis, SMS Medical College and Hospital, Jaipur, Rajasthan, India, India.
Koushik TripathyDepartment of Ophthalmology, ASG Eye Hospital, Kolkata, West Bengal, India.
Anita HarshDepartment of Pathology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Kamlesh KhilnaniDepartment of Ophthalmology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Kuldeep MendirattaDepartment of Radiodiagnosis, SMS Medical College and Hospital, Jaipur, Rajasthan, India, India.
Sunita AgarwalDepartment of Otorhinolaryngology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Jugal Kishore ChouhanDepartment of Ophthalmology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Sudhir BhandariDepartment of Medicine, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Sawai ManSingh Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the clinical profile and magnetic resonance imaging (MRI) features in patients of COVID-19-associated rhino-orbital-cerebral mucormycosis (CA-ROCM) with orbital involvement and perform a clinicoradiological correlation.

methodsA cross-sectional study was performed at a tertiary care center in north India from May 2021 to June 2021. Consecutive patients with clinical, nasal endoscopic, and/or microbiological evidence of CA-ROCM underwent MRI of paranasal sinuses, orbit, and brain as per the study protocol. Orbital MRI findings were studied in detail and were correlated with clinical signs.

resultsTwo hundred and seventy patients were studied. The mean age was 48.4 (± 16.82) years. A male predilection was noted (male:female = 1.77). Orbital involvement was seen in 146 (54%) patients on clinical evaluation and in 184 (68%) patients on MRI. Unilateral orbital involvement was more common (134; 92%). The most common presenting symptom was periorbital and/or facial pain (141; 52.2%) and the most common clinical sign was periorbital edema (116; 43%). The most common MRI finding was suggestive of orbital cellulitis (160; 59%). Orbital compartment syndrome was found in 17 (6.3%) patients. The inter-rater agreement between clinical and radiological assessments to detect the involvement of infraorbital nerve and frontal nerve was found to be 85.56%, (κ 0.621) and 93.70% (κ 0.776), respectively. The diagnostic accuracy, sensitivity, and specificity of MRI to detect medial orbital wall defect were found to be 87.9%, 65%, and 97%, respectively.

conclusionOrbital imaging features of a cohort of ROCM patients have been presented with clinicoradiological correlation.

Indexed as

COVID-19MucormycosisOrbital CellulitisOrbital DiseasesCross-Sectional StudiesFemaleHumansIndiaMagnetic Resonance ImagingMaleMiddle AgedSARS-CoV-2COVID-19MRImucormycosisorbitalROCM

Identifiers

PMID35086254
PMCPMC9023945
OpenAlexW4210539811

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.