ArticleIndian journal of ophthalmology2022
Evaluation of retinal nerve fiber layer, ganglion cell layer, and optic nerve head morphological parameters in patients with obstructive sleep apnea and comparison with normal population.
Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype.Diabetes, obesity & metabolism · 2026Review
- Multimodal neuro-ophthalmologic changes and the impact of CPAP therapy in severe obstructive sleep apnea: a prospective OCT, OCTA, and visual field study.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Interactive effects of retinal biomarkers and sleep on cognition: longitudinal evidence from community-dwelling older adults.GeroScience · 2026Article
- Rating Scales for Obstructive Sleep Apnea Syndrome: The Importance of a Comprehensive Assessment.Cureus · 2026Review
- Multimodal Assessment of Ocular Parameters in Patients with Severe Obstructive Sleep Apnea with Emphasis on Retinal Structural Changes.Life (Basel, Switzerland) · 2025Article
- Commentary: Obstructive sleep apnoea as a risk factor for glaucoma.Indian journal of ophthalmology · 2022Article
- Retinochoroidal structural alterations in obstructive sleep apnea: A spectral domain optical coherence tomography study.Taiwan journal of ophthalmologyArticle
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4 authors.
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Abstract
purposeTo compare the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), and optic nerve head (ONH) morphological parameters between obstructive sleep apnea (OSA) patients and age-matched controls using spectral domain optical coherence tomography (SD-OCT).
methodsThis case control study was conducted in a multi-specialty tertiary care hospital from 2014 to 2016. Patients diagnosed to have OSA by overnight polysomnography were included in the study. Fifty eyes of 25 OSA patients with clinically normal optic disc were compared with 50 eyes of age-matched controls. The study population underwent detailed ophthalmological evaluation including SD-OCT.
resultsThere was significant thinning of the superior, inferior, and average RNFL in the OSA group when compared to controls. GCL analysis also showed a significant thinning of the six sectors as well as average and minimum ganglion cell layer + inner plexiform layer in OSA patients. The optic nerve head rim area was significantly decreased in OSA patients when compared to controls.
conclusionOSA patients even with clinically normal optic disc showed significant decrease in the RNFL thickness, GCL thickness, and rim area when compared to age-matched controls. Hence, these patients constitute a high-risk population who need to be regularly screened and followed up for ocular co-morbidities.
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