Evidence map›Paper›PMID 35085623›Full record

SynthesisAdvanced drug delivery reviews2022

Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases.

Dasia Aldarondo, Elizabeth Wayne

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Advanced drug delivery reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Oxidized mRNA Lipid Nanoparticles forAdvanced functional materials · 2024
    Article
  11. Article
  12. Article
  13. Monocyte regulation by gut microbial signals.Trends in microbiology · 2023
    Review
  14. Review
  15. Harnessing Biomaterials for Immunomodulatory-Driven Tissue Engineering.Regenerative engineering and translational medicine · 2023
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dasia AldarondoDepartment of Chemical Engineering and Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Elizabeth WayneDepartment of Chemical Engineering and Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: ewayne@andrew.cmu.edu.
Carnegie Mellon University · US

Funding

Elucidating spatial and temporal dynamics of macrophage polarization using bioluminescence microscopyR35GM142957 · NIGMS · UNIVERSITY OF WASHINGTON · PI WAYNE, ELIZABETH C · 2021 to 2025
$1.8M
Interinstitutional Program in Cell and Molecular Biology: A Graduate Training Path to Promote Traditional and Non-Traditional Professional OutcomesT32GM133353 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRODSKY, JEFFREY L., MURRAY, SANDRA ANN · 2020 to 2024
$1.5M
NIGMS NIH HHS R35 GM142957NIGMS NIH HHS T32 GM133353
6 · The paper itself

Abstract

Due to the increasing population of individuals with cardiovascular diseases and related comorbidities, there is an increasing need for development of synergistic therapeutics. Monocytes are implicated in a broad spectrum of diseases and can serve as a focal point for therapeutic targeting. This review discusses the role of monocytes in cardiovascular diseases and highlights trends in monocyte targets nanoparticles in three cardiovascular-related diseases: Diabetes, Atherosclerosis, and HIV. Finally, the review offers perspectives on how to develop nanoparticle monocyte targeting strategies that can be beneficial for treating co-morbidities.

Indexed as

AtherosclerosisCardiovascular DiseasesComorbidityDiabetes MellitusHIV InfectionsHumansMacrophagesMonocytesNanoparticle Drug Delivery SystemPharmacokineticsPharmacologyNanoparticle Drug Delivery System

Identifiers

PMID35085623
PMCPMC9359644
OpenAlexW4207053095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.