Evidence map›Paper›PMID 35085366›Full record

SynthesisPloS one2022

Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis.

Sohail Akhtar, Jamal Abdul Nasir, Aqsa Ali, Mubeen Asghar, Rizwana Majeed, Aqsa Sarwar

Expression of concernOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 50 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 9 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 9 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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  8. Antibiotic Resistance during COVID-19: A Systematic Review.International journal of environmental research and public health · 2022
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  13. Frequency, Predictive Factors, and Burden of Gastrointestinal Symptoms in Patients With Type 2 Diabetes.JGH open : an open access journal of gastroenterology and hepatology · 2026
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  18. Prevalence, predictors, barriers and facilitators of self-monitoring of blood glucose in patients with type 2 diabetes: A multicentre cross-sectional study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sohail AkhtarDepartment of Mathematics and Statistics, The University of Haripur, Haripur, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0003-4870-152X
Jamal Abdul NasirDepartment of Statistics, GC University Lahore, Lahore, Pakistan.
Aqsa AliDepartment of Statistics, GC University Lahore, Lahore, Pakistan.
Mubeen AsgharDepartment of Statistics, GC University Lahore, Lahore, Pakistan.
Rizwana MajeedDepartment of Statistics, GC University Lahore, Lahore, Pakistan.
Aqsa SarwarDepartment of Statistics, GC University Lahore, Lahore, Pakistan.
Government College University, Lahore · PKUniversity of Haripur · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe main purpose of this study was to investigate the pooled prevalence of prediabetes and type-2 diabetes in the general population of Malaysia.

methodWe systematically searched Medline (PubMed), Embase, Web of Science, Google Scholar and Malaysian Journals Online to identify relevant studies published between January 1, 1995, and November 30, 2021, on the prevalence of type-2 diabetes in Malaysia. Random-effects meta-analyses were used to obtain the pooled prevalence of diabetes and prediabetes. Subgroup analyses also used to analyze to the potential sources of heterogeneity. Meta- regression was carried to assess associations between study characteristics and diabetes prevalence. Three independent authors selected studies and conducted the quality assessment. The quality of the final evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

resultsOf 2689 potentially relevant studies, 786 titles and abstract were screened. Fifteen studies with 103063 individuals were eligible to be included in the meta-analyses. The pooled prevalence of diabetes was 14.39% (95% CI, 12.51%-16.38%; I2 = 98.4%, 103063 participants from 15 studies). The pooled prevalence of prediabetes was 11.62% (95% CI, 7.17%-16.97%; I2 = 99.8, 88702 participants from 9 studies). The subgroup analysis showed statistically significant differences in diabetes prevalence by the ethical sub-populations with highest in Indians (25.10%; 95% CI, 20.19%-30.35%), followed by Malays (15.25%; 95% CI, 11.59%-19.29%), Chinese (12.87%; 95% CI, 9.73%-16.37%), Bumiputeras (8.62%; 95% CI, 5.41%-12.47%) and others (6.91%; 95% CI, 5.71%-8.19%). There was no evidence of publication bias, although heterogeneity was high (I2 ranged from 0.00% to 99·8%). The quality of evidence based on GRADE was low.

conclusionsResults of this study suggest that a high prevalence of prediabetes and diabetes in Malaysia. The diabetes prevalence is associated with time period and increasing age. The Malaysian government should develop a comprehensive approach and strategy to enhance diabetes awareness, control, prevention, and treatment.

trial registrationTrial registration no. PROSPERO CRD42021255894; https://clinicaltrials.gov/.

Indexed as

Diabetes Mellitus, Type 2Prediabetic StateHumansMalaysiaPrevalence

Identifiers

PMID35085366
PMCPMC8794132
OpenAlexW4210769721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.