ArticlePloS one2022
Quality of life and associated factors among patients with epilepsy at specialized hospitals, Northwest Ethiopia; 2019.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Health-related quality of life and its predictors among epilepsy patients in Ethiopia: Systematic review and meta-analysis.PloS one · 2025Pooled it
- Quality of life and associated factors among people with epilepsy in Ethiopia: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- A systematic review of the effectiveness of epilepsy education programs on knowledge, attitudes, and skills among primary school learners.Frontiers in neurology · 2024Pooled it
- Prevalence and factors associated with depressive symptoms among patients with epilepsy in Ethiopia: a national-based systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- A systematic review of non-invasive biomarkers for seizure forecasting in pediatric epilepsy patients.Frontiers in neurologyPooled it
- Development, psychometric validation, and correlates of the 15-item quality of life in epilepsy scale (QOLIE-15).Scientific reports · 2026Article
- Health-related quality of life and associated factors among patients living with epilepsy of Mekelle City Hospitals, Northern Ethiopia: a multicenter observational study.Health and quality of life outcomes · 2026Observational
- Observational
- Measuring Health-related Quality of Life in Pediatric Patients with Ultra-rare Diseases: A Multicenter Study.Current medicinal chemistry · 2026Article
- Quality of life, depression, daytime sleepiness and fatigue in Omani people with epilepsy: a cross-sectional study.BMC neurology · 2025Article
- Daidzin Enhances the Anticonvulsion Effects of Carbamazepine and Diazepam, Possibly Through Voltage-Gated Sodium Channels and GABAMolecular neurobiology · 2025Article
- Quality of life in adults with refractory epilepsy in Thailand: a multicenter upcountry nationwide study.BMC public health · 2025Article
- Multicentric study of adherence to antiseizure medications among adults with epilepsy attended in neurology departments in Burkina Faso.Epilepsia open · 2025Article
- Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study.BMC research notes · 2025Article
- Cognitive dysfunction and its associated factors in patients with epilepsy at referral hospitals in the Amhara region: an institutional-based cross-sectional study.Frontiers in neurology · 2025Article
- Adherence to Epilepsy's Medical Recommendations.Brain sciences · 2024Article
- Determinants of epilepsy among outpatients in public health institutions of Dawo district, South West Shoa Zone, Oromia, Ethiopia, 2023: an institutional-based unmatched case-control study.Frontiers in neurology · 2024Article
- Health related quality of life in a Saudi population of patients with epilepsy.Neurosciences (Riyadh, Saudi Arabia) · 2023Article
- The long-term outcomes of patients with negative prolonged ambulatory electroencephalography tests: A cross-sectional follow-up study.Health open research · 2023Article
- Detecting Reasons for Nonadherence to Medication in Adults with Epilepsy: A Review of Self-Report Measures and Key Predictors.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpilepsy is a chronic non-communicable brain disorder and the second most burdensome disease in terms of disability-adjusted life years which is characterized by recurrent epileptic seizures, and a constant threat to the quality of life of the patient. Nearly 80% of people with epilepsy live in low- and middle-income countries and the risk of premature death in people with epilepsy is up to three times higher than for the general population. In many parts of the world, people with epilepsy and their families suffer from stigma and discrimination. This study was aimed to assess the quality of life and associated factors among adult people living with epilepsy using the world health organization quality of life assessment tool.
methodsInstitution-based cross-sectional study design was conducted on 419 epileptic patients using a systematic random sampling technique. The data were collected using the WHOQOL-BREF questionnaire. The data were entered into EpiData version 3.1 and exported to SPSS version 25 software for further analysis and bivariate and multivariable binary logistic regression analyses were done to identify factors associated with the dependent variable. The level of significance was declared as P value <0.05.
resultA total of 402 epileptic patients with a median age of 28 years were involved in the study. The result of this study was revealed that 47.8% (95% CI: 42%, 52%) of the respondents had poor quality of life. Respondents who were in the middle age group (AOR = 0.36, 95% CI: 0.19, 0.70), lower educational level (AOR = 3.11, 95%CI: 1.35, 7.15), those who had low drug adherence (AOR = 8.36, 95%CI: (2.41, 28.98) comorbid anxiety, (AOR = 3.63, 95% CI: 2.55, 8.42) and depression (AOR = 3.85, 95% CI: 2.16, 6.82) were found to be significantly associated with poor quality of life of epilepsy patients.
conclusionThis study revealed that almost one in two epileptic patients had poor quality of life. Age of the respondents, lower educational level, comorbid anxiety and depression, and lower adherence to drugs were significantly associated with poor quality of life. Therefore, health institutions and clinicians should not focus only on the treatment of the disease itself rather they should address diseases' impact on the quality of life of patients.
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