Evidence map›Paper›PMID 35085230›Full record

ArticlePLoS computational biology2022

Project-based learning course on metabolic network modelling in computational systems biology.

Thomas Sauter, Tamara Bintener, Ali Kishk, Luana Presta, Tessy Prohaska, Daniel Guignard, Ni Zeng, Claudia Cipriani, Sundas Arshad, Thomas Pfau and 2 more

Abstract read
In one paragraph

Article in PLoS computational biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas SauterSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-8225-2954
Tamara BintenerSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-8218-666X
Ali KishkSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0003-3710-5909
Luana PrestaSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-6482-6758
Tessy ProhaskaSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.
Daniel GuignardSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.
Ni ZengSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.
Claudia CiprianiSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-8618-4717
Sundas ArshadSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0002-1165-2114
Thomas PfauSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-5048-2923
Patricia Martins CondeSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0003-2246-5469
Maria Pires PachecoSystems Biology Group, Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-7956-8093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Project-based learning (PBL) is a dynamic student-centred teaching method that encourages students to solve real-life problems while fostering engagement and critical thinking. Here, we report on a PBL course on metabolic network modelling that has been running for several years within the Master in Integrated Systems Biology (MISB) at the University of Luxembourg. This 2-week full-time block course comprises an introduction into the core concepts and methods of constraint-based modelling (CBM), applied to toy models and large-scale networks alongside the preparation of individual student projects in week 1 and, in week 2, the presentation and execution of these projects. We describe in detail the schedule and content of the course, exemplary student projects, and reflect on outcomes and lessons learned. PBL requires the full engagement of students and teachers and gives a rewarding teaching experience. The presented course can serve as a role model and inspiration for other similar courses.

Indexed as

Metabolic Networks and PathwaysProblem-Based LearningHumansStudentsSystems BiologyThinking

Identifiers

PMID35085230
PMCPMC8794106

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.