Evidence map›Paper›PMID 35085059›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Genetic Ancestry to Improve Precision of Race/Ethnicity-based Lung Function Equations in Children.

Jonathan Witonsky, Jennifer R Elhawary, Celeste Eng, José R Rodríguez-Santana, Luisa N Borrell, Esteban G Burchard

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. FEVThe European respiratory journal · 2024
    Article
  6. Article
  7. Review
  8. Reply by McCormackAmerican journal of respiratory and critical care medicine · 2022
    Article
  9. U.S. Occupational Historical Perspective on Race and Lung Function.American journal of respiratory and critical care medicine · 2022
    Article
  10. Genetic Ancestry Has the Same Major Problems as Phenotypic Ancestry.American journal of respiratory and critical care medicine · 2022
    Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jonathan WitonskyUniversity of California San Francisco San Francisco, California.
Jennifer R ElhawaryUniversity of California San Francisco San Francisco, California.
Celeste EngUniversity of California San Francisco San Francisco, California.
José R Rodríguez-SantanaCentro de Neumología Pediátrica San Juan, Puerto Rico.
Luisa N BorrellCity University of New York New York, New York.
Esteban G BurchardUniversity of California San Francisco San Francisco, California.

Funding

NRSA Training CoreTL1TR001871 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SOMSOUK, MA · 2016 to 2025
$10.1M
The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Optimizing imputation for diverse populations in a distributed frameworkU01HG009080 · NHGRI · STANFORD UNIVERSITY · PI KENNY, EIMEAR ELIZABETH · 2016 to 2020
$5.2M
Transcriptomic and Pharmacogenetic Asthma Endotypes in Minority ChildrenR01HL135156 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A, ZIV, ELAD · 2017 to 2021
$4.1M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Genetic Control of Airway Epithelium Gene Expression in Childhood AsthmaticsR01HL128439 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2015 to 2019
$3.1M
Epigenomics of asthma risk factors and clinical subtypes in minority childrenR01HL155024 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BORRELL, LUISA N, ZAITLEN, NOAH A · 2021 to 2024
$2.9M
Integrative Analyses to Uncover Biological Mechanisms Mediating Gene Associations with Asthma Drug Response Among Minority ChildrenR01HL141992 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BURCHARD, ESTEBAN GONZALEZ, HIMES, BLANCA E · 2018 to 2019
$855k
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse ChildrenR21ES024844 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, GAUDERMAN, WILLIAM JAMES · 2015 to 2017
$509k
Epigenetics of Socio-Environmental Effects on Asthma in MinoritiesR56MD013312 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, ZAITLEN, NOAH A · 2018 to 2018
$458k
NCATS NIH HHS TL1 TR001871NHGRI NIH HHS U01HG009080NHLBI NIH HHS 1X01HL134589NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01HL117004NHLBI NIH HHS R01HL128439NHLBI NIH HHS R01 HL135156NHLBI NIH HHS R01HL135156NHLBI NIH HHS R01 HL141992NHLBI NIH HHS R01HL141992NHLBI NIH HHS R01 HL155024NHLBI NIH HHS R01HL155024NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R01ES015794NIEHS NIH HHS R21 ES024844NIEHS NIH HHS R21ES24844NIGMS NIH HHS T32GM007546NIMHD NIH HHS R01 MD010443NIMHD NIH HHS R01MD010443NIMHD NIH HHS R56 MD013312NIMHD NIH HHS R56MD013312
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EthnicityWhite PeopleBlack or African AmericanChildHumansLungRespiratory Physiological Phenomena

Identifiers

PMID35085059
PMCPMC12985403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.