Evidence map›Paper›PMID 35084775›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022

Mitochondria modulate ameloblast Ca

Veronica Costiniti, Guilherme H S Bomfim, Maria Neginskaya, Ga-Yeon Son, Erna Mitaishvili, Marta Giacomello, Evgeny Pavlov, Rodrigo S Lacruz

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Mathematical Modeling of Calcium Dynamics in Ameloblasts.Calcified tissue international · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Roles of calcium in ameloblasts during tooth development: A scoping review.Journal of Taibah University Medical Sciences · 2025
    Review
  7. Genes & diseases · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Overexpression ofCells · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Veronica CostinitiDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.ORCID 0000-0002-8472-7797
Guilherme H S BomfimDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.
Maria NeginskayaDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.
Ga-Yeon SonDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.
Erna MitaishviliDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.
Marta GiacomelloDepartment of Biology, University of Padova, Padua, Italy.
Evgeny PavlovDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.
Rodrigo S LacruzDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA.
New York University · USUniversity of Padua · IT

Funding

Redox and Ca2+ signaling regulation of enamel mineralizationR01DE027679 · NIDCR · NEW YORK UNIVERSITY · PI Rodrigo S. Lacruz · 2018 to 2026
$3.3M
Ca2+ signaling via SOCE in the pathogenesis of Sjögren’s syndromeR01DE027981 · NIDCR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN, LACRUZ, RODRIGO S. · 2019 to 2023
$2.7M
Calcium Control of Enamel DevelopmentR01DE025639 · NIDCR · NEW YORK UNIVERSITY · PI LACRUZ, RODRIGO S. · 2016 to 2020
$2.0M
Molecular composition of the mitochondrial permeability transition poreR01GM115570 · NIGMS · NEW YORK UNIVERSITY · PI PAVLOV, EVGENY · 2016 to 2020
$1.8M
NIDCR NIH HHS R01 DE025639NIDCR NIH HHS R01 DE027679NIDCR NIH HHS R01 DE027981NIGMS NIH HHS R01 GM115570
6 · The paper itself

Abstract

The role of mitochondria in enamel, the most mineralized tissue in the body, is poorly defined. Enamel is formed by ameloblast cells in two main sequential stages known as secretory and maturation. Defining the physiological features of each stage is essential to understand mineralization. Here, we analyzed functional features of mitochondria in rat primary secretory and maturation-stage ameloblasts focusing on their role in Ca

Indexed as

Adenosine TriphosphateAmeloblastsAnimalsCalciumCalcium ChannelsCalcium SignalingCells, CulturedCytosolEndoplasmic ReticulumMitochondriaRatsRats, Sprague-DawleyAdenosine TriphosphateCalciumCalcium ChannelsenamelmaturationMCUmitochondriasecretory

Identifiers

PMID35084775
PMCPMC8852362
OpenAlexW4210306763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.