Evidence map›Paper›PMID 35084641›Full record

ArticleJournal of clinical monitoring and computing2022

Accuracy of a point-of-care blood lactate measurement device in a prehospital setting.

Louise Houlberg Walther, Floor Zegers, Mads Nybo, Christian Backer Mogensen, Erika Frischknecht Christensen, Annmarie Touborg Lassen, Søren Mikkelsen

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical monitoring and computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. The use and impact of prehospital blood lactate measurements in acute non-traumatic patients: a systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024
    Pooled it
  2. Trial
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  4. Article
  5. Article
  6. Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term-births in northern Uganda: A cross sectional analytical study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  7. Review
  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Louise Houlberg WaltherThe Prehospital Research Unit, Region of Southern Denmark, Odense University Hospital, Odense, Denmark. louise.houlberg.walther@rsyd.dk.ORCID 0000-0001-8555-363X
Floor ZegersCentre for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-8318-5332
Mads NyboDepartment of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-3029-2855
Christian Backer MogensenEmergency Medicine Research Unit, Hospital Sønderjylland, University Hospital of Southern Denmark, Aabenraa, Denmark.ORCID 0000-0002-8254-089X
Erika Frischknecht ChristensenCentre for Prehospital and Emergency Research, Aalborg University Hospital and Institute for Clinical Medicine, Aalborg University, Aalborg, Denmark.ORCID 0000-0003-3673-9694
Annmarie Touborg LassenDepartment of Emergency Medicine, Odense University Hospital, Odense, Denmark.ORCID 0000-0003-4942-6152
Søren MikkelsenThe Prehospital Research Unit, Region of Southern Denmark, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-5187-7027
University of Southern Denmark · DKOdense University Hospital · DKAalborg University Hospital · DKSygehus Sønderjylland · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Point-of-care blood lactate is a promising prognostic biomarker of short-term mortality risk. Portable lactate meters need validation in the prehospital setting before widespread implementation and it is unknown whether the mode of sampling (arterial, capillary or venous) matters. This study aims to compare the StatStrip Xpress Lactate Meter's (SSX) accuracy to a validated blood gas analyser, ABL90 FLEX (ABL90), in arterial samples in the prehospital environment and to determine if lactate levels measured in venous and capillary blood samples are sufficiently accurate compared to arterial lactate levels. Patients with arterial samples drawn by the prehospital anaesthesiologist for any reason were eligible for inclusion. Simultaneously, three blood samples (arterial, capillary and venous) were analysed on SSX and arterial blood on ABL90. Measurements of agreements were evaluated by Lin's concordance correlations coefficient (CCC) and Bland-Altman Plots. One-hundred-and-eleven patients were included. SSX showed good accuracy compared to ABL90 in arterial samples with a CCC of 0.92 (95% CI 0.90-0.94). Compared to the arterial samples measured on ABL90, venous samples analysed on SSX showed higher agreement than capillary samples analysed on SSX with CCCs of 0.88 (95% CI 0.85-0.91) and 0.79 (95% CI 0.72-0.85), respectively. Bland-Altman plots showed that SSX lactate measurements in arterial, venous and capillary blood samples all had systematically negative biases compared to ABL90. We conclude that the SSX is accurate in our prehospital setting. Venous samples should be preferred over capillary samples, when arterial samples cannot be obtained.

Indexed as

Emergency Medical ServicesPoint-of-Care SystemsBlood Gas AnalysisHumansLactic AcidVeinsLactic AcidLactatePoint-of-carePortable devicePrehospitalStatStrip

Identifiers

PMID35084641
PMCPMC9637595
OpenAlexW4210441871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.