ArticleEuropean journal of histochemistry : EJH2022
Evaluation of biocompatibility, osteointegration and biomechanical properties of the new Calcemex® cement: An <em>in vivo</em> study.
Article in European journal of histochemistry : EJH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Advances in TCP-Modified PMMA Bone Cements: Relating Microstructure to Mechanical, Biological and Functional Performance-Systematic Review.Materials (Basel, Switzerland) · 2026Review
- Bone void filler materials for augmentation in comminuted fractures: a comprehensive review.Journal of orthopaedic surgery and research · 2025Review
- Efficacy of Cal-Cemex as bone substitute for tibial plateau fractures.Journal of orthopaedic surgery and research · 2023Article
- Different Modification Methods of Poly Methyl Methacrylate (PMMA) Bone Cement for Orthopedic Surgery Applications.The archives of bone and joint surgery · 2023Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mixture of polymethylmethacrylate (PMMA) and β-tricalciumphospate (β-TCP) is the most widely used bone graft. Common features of bone cement are the biocompatibility, bioactivity, mechanical stability and ability to fuse with the host's bone tissue. However, there are still few studies that have evaluated these characteristics in vivo. Our study aims to acquire these parameters, using an animal model with functional characteristics similar to those of humans. The analyzed cement is Calcemex®, evaluated both in compact and fluid formulation. The chosen animal models were 5 pigs, treated with femoral and tibial implants of Calcemex® samples. After one year, the pigs were sacrificed and the specimens explanted for morphological, histological, ultrastructural and mechanical evaluations. For both formulations, the investigation highlighted the absence of foreign body reactions in the host, the histological integration with the surrounding tissues and the preservation of mechanical compression resistance.
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Registered trials
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