Evidence map›Paper›PMID 35083843›Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2022

The role of the androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments.

Varun S Venkatesh, Mathis Grossmann, Jeffrey D Zajac, Rachel A Davey

Open access · hybridAbstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. How Food Choices Impact on Male Fertility.Current nutrition reports · 2023
    Review
  7. Review
  8. The role of the androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Varun S VenkateshDepartment of Medicine, Austin Health, University of Melbourne, Heidelberg, Victoria.ORCID 0000-0002-1295-0033
Mathis GrossmannDepartment of Medicine, Austin Health, University of Melbourne, Heidelberg, Victoria.
Jeffrey D ZajacDepartment of Medicine, Austin Health, University of Melbourne, Heidelberg, Victoria.
Rachel A DaveyDepartment of Medicine, Austin Health, University of Melbourne, Heidelberg, Victoria.
The University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is associated with hypothalamic-pituitary-testicular axis dysregulation in males. Here, we summarize recent evidence derived from clinical trials and studies in preclinical animal models regarding the role of androgen receptor (AR) signaling in the pathophysiology of males with obesity. We also discuss therapeutic strategies targeting the AR for the treatment of obesity and their limitations and provide insight into the future research necessary to advance this field.

Indexed as

Receptors, AndrogenTestosteroneAnimalsHumansMaleObesityReceptors, AndrogenTestosteronefatmenobesitytestosterone

Identifiers

PMID35083843
PMCPMC9286619
OpenAlexW4210812833

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.