Evidence map›Paper›PMID 35083780›Full record

ArticleEuropean journal of cancer care2022

The prognostic value of the 12-, 6-, 3- and 1-month 'Surprise Question' in cancer patients: A prospective cohort study in three hospitals.

Arianne Stoppelenburg, Müzeyyen Arslan, Catherine Owusuaa, Nicolette Gunnink, Yvette M van der Linden, Saskia A C Luelmo, Jetske Meerum-Terwogt, Annemieke van der Padt-Pruijsten, Daan Nieboer, Agnes van der Heide

Abstract read
In one paragraph

Article in European journal of cancer care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arianne StoppelenburgDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-6377-1599
Müzeyyen ArslanDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5454-8926
Catherine OwusuaaDepartment of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-3695-4466
Nicolette GunninkDepartment of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
Yvette M van der LindenCenter of Expertise Palliative Care, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-9003-6124
Saskia A C LuelmoCenter of Expertise Palliative Care, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-9298-2878
Jetske Meerum-TerwogtDepartment of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
Annemieke van der Padt-PruijstenDepartment of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5186-865X
Daan NieboerDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-4403-6537
Agnes van der HeideDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5584-4305

Funding

Erasmus Medical Center (MRACE), Rotterdam, the Netherlands Grant number 2011-11112ZonMw, the Netherlands Organisation for Health Research and Development Grant number 11510031
6 · The paper itself

Abstract

objectiveThis prospective study aimed to evaluate the performance of the 'Surprise Question' (SQ) 'Would I be surprised if this patient died in the next 12 months?' in predicting survival of 12, 6, 3 and 1 month(s), respectively, in hospitalised patients with cancer.

methodsIn three hospitals, physicians were asked to answer SQs for 12/6/3/1 month(s) for inpatients with cancer. Sensitivity, specificity, positive and negative predictive values were calculated.

resultsA total of 783 patients were included, of whom 51% died in the 12-month period after inclusion. Sensitivity of the SQ predicting death within 12 months was 0.79, specificity was 0.66, the positive predictive value was 0.71 and the negative predictive value was 0.75. When the SQ concerned a shorter survival period, sensitivities and positive predictive values decreased, whereas specificities and negative predictive values increased. In multivariable logistic regression analysis, the SQ was significantly associated with mortality (OR 3.93, 95% CI 2.70-5.71, p < 0.01).

conclusionsThe 12-month SQ predicts death in patients with cancer admitted to the hospital reasonably well. Shortening the timeframe decreases sensitivities and increases specificities. The four surprise questions may help to identify patients for whom palliative care is indicated.

Indexed as

NeoplasmsPalliative CareHospitalsHumansPrognosisProspective Studiescancerhospitalobservational studypalliative careprognosisSurprise Question

Identifiers

PMID35083780
PMCPMC9788313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.