ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2022
A Scoping Review of the Classification, Diagnosis, and Management of Hepatic Adenomas.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Turner Syndrome and Hepatic Adenomas: A Case Report.Cureus · 2025Article
- Hepatic hemangiomas mimicking gastrointestinal stromal tumors: A case report.World journal of clinical cases · 2025Article
- Article
- Living-Donor Liver Transplantation for a Large Hepatocellular Carcinoma in a Genetically Identical Twin Sister.Zeitschrift fur Gastroenterologie · 2024Article
- Multimodal imaging study of hepatic perivascular epithelioid cell tumors: a case report.Frontiers in medicine · 2023Article
- [Liver involvement in endocrine diseases].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundHepatic adenomas (HA), or hepatocellular adenomas, are benign, solid liver lesions that develop in otherwise normal livers, often in the setting of increased estrogen levels. While considered a benign tumor, there is a risk for substantial complications such as hemorrhage and malignant transformation. We review the diagnosis, classification, and potential therapeutic management options for patients with HA.
methodsA scoping narrative review was conducted based on recent literature regarding classification, diagnosis, and management of HA.
resultsWhile HAs are typically considered benign, complications such as hemorrhage and malignant transformation may occur in approximately 25% and 5% of patients, respectively. Recent advances in imaging and molecular profiling have allowed for the classification of HAs into subtypes allowing for patient risk stratification that helps guide management. Surgical resection should be considered in asymptomatic patients who are male, have an adenoma ≥5 cm in diameter, or have the β-catenin-activated subtype due to an increased risk of hemorrhage and/or malignant transformation.
conclusionMolecular profiling has aided in the stratification of patients relative to the risk of complications to predict better the potential behavior of HAs.
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