Evidence map›Paper›PMID 35083663›Full record

ArticleMolecular neurobiology2022

The 40-Hz White Light-Emitting Diode (LED) Improves the Structure-Function of the Brain Mitochondrial KATP Channel and Respiratory Chain Activities in Amyloid Beta Toxicity.

Maryam Nazari, Taha Vajed-Samiei, Nihad Torabi, Javad Fahanik-Babaei, Reza Saghiri, Fariba Khodagholi, Afsaneh Eliassi

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Gamma sensory stimulation in mild Alzheimer's dementia: An open-label extension study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Light Therapy in Chronic Migraine.Current pain and headache reports · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Maryam NazariNeurophysiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Taha Vajed-SamieiSchool of Electrical and Computer Engineering, Tehran University, Tehran, Iran.
Nihad TorabiDepartment of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Javad Fahanik-BabaeiElectrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Reza SaghiriDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Fariba KhodagholiNeuroscience Research Center, Shahid Beheshti University of Medical Sciences, Evin, Tehran, Iran.
Afsaneh EliassiNeurophysiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. af.eliassi@sbmu.ac.ir.ORCID http://orcid.org/0000-0002-4899-3430
Shahid Beheshti University of Medical Sciences · IRPasteur Institute of Iran · IRTehran University of Medical Sciences · IRUniversity of Tehran · IRUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been described that using noninvasive exposure to 40-Hz white light LED reduces amyloid-beta, a peptide thought to initiate neurotoxic events in Alzheimer's disease (AD). However, the mechanisms remain to be identified. Since AD impairs mitochondrial potassium channels and respiratory chain activity, the objectives of the current study were to determine the effect of 40-Hz white light LED on structure-function of mitoK

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAdenosine TriphosphateAnimalsBrainElectron TransportKATP ChannelsPotassium ChannelsRatsReactive Oxygen SpeciesAdenosine TriphosphateAmyloid beta-PeptidesKATP Channelsmitochondrial K(ATP) channelPotassium ChannelsReactive Oxygen SpeciesAlzheimer’s diseaseLED therapyMitochondriaMitoKATP channelRespiratory chain activity

Identifiers

PMID35083663
OpenAlexW4210570714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.