Observational studyEuropean journal of epidemiology2022
Risk factors for COVID-19-related death, hospitalization and intensive care: a population-wide study of all inhabitants in Stockholm.
Observational study in European journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Time-Series modeling for predicting mortality risk in intensive care unit patients with pulmonary inflammation.Frontiers in medicine · 2026Article
- The role of natural outdoor environment on COVID-19 mortality and hospitalisations among older community-dwellers in the pre-vaccination period: the Register RELOC-AGE cohort study in Sweden.BMC public health · 2025Article
- Unrecognised COVID-19 deaths in central Europe: The importance of cause-of-death certification for the COVID-19 burden assessment.PloS one · 2024Article
- Three Years of the Coronavirus Disease 2019 Pandemic in a European Region: A Population-Based Longitudinal Assessment in Madrid Between 2020 and 2022.Open forum infectious diseases · 2024Article
- Interpretability-based machine learning for predicting the risk of death from pulmonary inflammation in Chinese intensive care unit patients.Frontiers in medicine · 2024Article
- Association Between Artificial Intelligence Based Chest Computed Tomography and Clinical/Laboratory Characteristics with Severity and Mortality in COVID-19 Hospitalized Patients.Journal of inflammation research · 2024Article
- Does atrial fibrillation affect prognosis in hospitalised COVID-19 patients? A multicentre historical cohort study in the Netherlands.BMJ open · 2023Observational
- Phase Angle and Handgrip Strength as Predictors of Clinical Outcomes in Hospitalized COVID-19 Patients.Nutrients · 2023Article
- COVID-19 and comedications in atrial fibrillation-a case-control study in Stockholm.European journal of epidemiology · 2023Article
- The Role of CRP POC Testing in the Fight against Antibiotic Overuse in European Primary Care: Recommendations from a European Expert Panel.Diagnostics (Basel, Switzerland) · 2023Article
- Individual and neighborhood risk factors of hospital admission and death during the COVID-19 pandemic: a population-based cohort study.BMC medicine · 2023Article
- Association of BMI with general health, working capacity recovered, and post-acute sequelae of COVID-19.Obesity (Silver Spring, Md.) · 2023Article
- Influence of obesity on incidence of thrombosis and disease severity in patients with COVID-19: From the CLOT-COVID study.Journal of cardiology · 2023Observational
- Drug-Drug Interactions among Patients Hospitalized with COVID-19 in Greece.Journal of clinical medicine · 2022Article
- Diabetes and COVID-19 testing, positivity, and mortality: A population-wide study in Northern Italy.Diabetes research and clinical practice · 2022Article
- Implementation of diabetes care and educational program via telemedicine in patients with COVID-19 in home isolation in Thailand: A real-worldexperience.Journal of diabetes investigation · 2022Article
- Article
- Risk Factors Associated with Mortality in COVID-19 Hospitalized Patients: Data from the Middle East.International journal of clinical practice · 2022Article
- COVID-19 vaccine booster significantly decreases the risk of intensive care unit hospitalization in heart failure patients during the Omicron variant wave: A population-based study.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the beginning of the Covid-19 pandemic, the scientific community has explored determinants of Covid 19 disease severity. However, the majority of studies are based on in-hospital patients with high risk of collider- or selection bias. The present investigation details risk factors associated with overall mortality, hospitalization and intensive care unit (ICU) admission in Covid-19 infections, with complete population coverage and high-resolution data on patient characteristics and comorbid conditions This population-based observational study comprises all residents 18 years and older in Stockholm Region-1.8 million inhabitants-using the real-time Covid-19 monitoring framework. The observation period lasted between March 1 to December 31, 2020. Hazard ratios (HR) for risk factors of Covid-19 disease severity were assessed using Cox proportional hazard models. In total, 3322 deaths, 11,508 hospitalizations and 1423 ICU-admissions related to Covid-19 occurred during the study period. Kidney failure, diabetes and obesity increased risk of mortality and so did heart failure and ischemic heart disease. However, atrial fibrillation and hypertension did not. Risk of hospitalization follow a similar pattern, whereas admission to intensive care differs; triage processes where clearly present as certain co-morbid conditions were associated with lower ICU admission. Observed differences in risk of mortality and hospitalization among patients with Covid 19 raise important questions about potentially protective comedication which will be further addressed using the real-time Covid-19 monitoring framework.
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