Evidence map›Paper›PMID 35083316›Full record

ArticleERJ open research2022

Epidemiology of interstitial lung diseases and their progressive-fibrosing behaviour in six European countries.

Ole Hilberg, Anna-Maria Hoffmann-Vold, Vanessa Smith, Demosthenes Bouros, Maritta Kilpeläinen, Julien Guiot, Antonio Morais, Susana Clemente, Zoe Daniil, Despina Papakosta and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06317831 (LetS Get fUnctional! FuNctional Status in pEople With intersTitial Lung Disease - the SUNSET Study), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06317831 recruitingnot on this mapstarted 2024, after this paper: background citation

LetS Get fUnctional! FuNctional Status in pEople With intersTitial Lung Disease - the SUNSET Study

Typeobservational_patient_registrySponsorAveiro UniversityRan2024 to 2028Enrolled150ConditionsInterstitial Lung Diseases
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Global epidemiology and burden of interstitial lung disease.The Lancet. Respiratory medicine · 2025
    Review
  11. Review
  12. The lung microbiome in interstitial lung disease.Breathe (Sheffield, England) · 2025
    Review
  13. The DSC Index: A new prognostic tool for evaluating functional status in interstitial lung disease.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ole HilbergIRS-centre, Lillebælt Hospital, Vejle, Denmark.
Anna-Maria Hoffmann-VoldDept of Rheumatology, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
Vanessa SmithDept of Rheumatology, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0001-6271-7945
Demosthenes BourosDept of Pneumonology, Athens Medical Centre, Maroussi, Greece.ORCID https://orcid.org/0000-0002-0685-0765
Maritta KilpeläinenDept of Pulmonary Diseases, Turku University Hospital and University of Turku, Turku, Finland.
Julien GuiotDept of Respiratory Medicine, Liege University Hospital Centre, Liege, Belgium.ORCID https://orcid.org/0000-0001-7800-1730
Antonio MoraisPulmonary Dept, Sao Joao University Hospital Centre, Porto, Portugal.ORCID https://orcid.org/0000-0001-8348-8651
Susana ClementePulmonary Dept, Beatriz Angelo Hospital, Loures, Portugal.
Zoe DaniilDept of Respiratory Medicine, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Despina PapakostaDept of Respiratory Medicine, Aristotle University of Thessaloniki, George Papanikolaou General Hospital, Thessaloniki, Greece.
Havard FretheimDept of Rheumatology, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
Sofia NevesPulmonary Dept, Vila Nova de Gaia/Espinho Hospital Centre, Vila Nova de Gaia, Portugal.
Tiago M AlfaroPulmonary Dept, Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.ORCID https://orcid.org/0000-0001-6490-0620
Katerina M AntoniouDept of Respiratory Medicine, Faculty of Medicine, University of Crete, Crete, Greece.
Neus ValvenyTrial Form Support S.L., Barcelona, Spain.
Guus AsijeeBoehringer Ingelheim B.V., Amsterdam, The Netherlands.
Stéphane SoulardBoehringer Ingelheim B.V., Amsterdam, The Netherlands.
Wim WuytsDept of Respiratory Medicine, Leuven University Hospital, Leuven, Belgium.ORCID https://orcid.org/0000-0001-9648-3497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PERSEIDS study aimed to estimate incidence/prevalence of interstitial lung diseases (ILDs), fibrosing interstitial lung diseases (F-ILDs), idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated ILD (SSc-ILD), other non-IPF F-ILDs and their progressive-fibrosing (PF) forms in six European countries, as current data are scarce. This retrospective, two-phase study used aggregate data (2014-2018). In Phase 1, incident/prevalent cases of ILDs above were identified from clinical databases through an algorithm based on codes/keywords, and incidence/prevalence was estimated. For non-IPF F-ILDs, the relative percentage of subtypes was also determined. In Phase 2, a subset of non-IPF F-ILD cases was manually reviewed to determine the percentage of PF behaviour and usual interstitial pneumonia-like (UIP-like) pattern. A weighted mean percentage of progression was calculated for each country and used to extrapolate incidence/prevalence of progressive-fibrosing ILDs (PF-ILDs). In 2018, incidence/10

Identifiers

PMID35083316
PMCPMC8784757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.