Evidence map›Paper›PMID 35083283›Full record

ReviewInflammatory intestinal diseases2021

Behcet's Disease: An In-Depth Review about Pathogenesis, Gastrointestinal Manifestations, and Management.

Anthony Nguyen, Shubhra Upadhyay, Muhammad Ali Javaid, Abdul Moiz Qureshi, Shahan Haseeb, Nismat Javed, Christopher Cormier, Asif Farooq, Abu Baker Sheikh

Open access · goldAbstract readReview
In one paragraph

Review in Inflammatory intestinal diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. The treatment principles and targets for intestinal Behcet's disease.Therapeutic advances in gastroenterology · 2023
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Anthony NguyenDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
Shubhra UpadhyayDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
Muhammad Ali JavaidDepartment of Internal Medicine, Dow Medical College, Karachi, Pakistan.
Abdul Moiz QureshiDepartment of Internal Medicine, Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Shahan HaseebDepartment of Internal Medicine, Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Nismat JavedDepartment of Internal Medicine, Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Christopher CormierDepartment of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
Asif FarooqDepartment of Family and Community Medicine, Texas Tech Health Sciences Center, Lubbock, Texas, USA.
Abu Baker SheikhDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
University of New Mexico · USShifa Tameer-e-Millat University · PKDow University of Health Sciences · PKTexas Tech University Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehcet's disease (BD) is a complex inflammatory vascular disorder that follows a relapsing-remitting course with diverse clinical manifestations. The prevalence of the disease varies throughout the globe and targets different age-groups. There are many variations of BD; however, intestinal BD is not only more common but has many signs and symptoms. SUMMARY: BD is a relapsing-remitting inflammatory vascular disorder with multiple system involvement, affecting vessels of all types and sizes that targets young adults. The etiology of BD is unknown but many factors including genetic mechanisms, vascular changes, hypercoagulability, and dysregulation of immune function are believed to be responsible. BD usually presents with signs and symptoms of ulcerative disease of the small intestine; endoscopy being consistent with the clinical manifestations. The mainstay of treatment depends upon the severity of the disease. Corticosteroids are recommended for severe forms of the disease and aminosalicylic acids are used in maintaining remission in mild to moderate forms of the disease. KEY MESSAGES: In this review, we have tried to summarize in the present review the clinical manifestations, differential diagnoses, and management of intestinal BD. Hopefully, this review will enable health policymakers to ponder over establishing clear endpoints for treatment, surveillance investigations, and creating robust algorithms.

Indexed as

Behcet's diseaseGastrointestinal involvementInflammatory vascular disorderManagementPathogenesis

Identifiers

PMID35083283
PMCPMC8740277
OpenAlexW3213581218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.