ReviewFrontiers in medicine2021
Emerging Progress in Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum: Challenges and Opportunities.
Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Treatment of Nausea and Vomiting With Zingiber officinale in Pregnancy: An Umbrella Review of Systematic Reviews With Meta-Synthesis.Phytotherapy research : PTR · 2026Pooled it
- Acupuncture for nausea and vomiting during pregnancy: an overview of systematic reviews.Frontiers in endocrinology · 2026Pooled it
- Efficacy and safety of acupressure in nausea and vomiting during pregnancy: a systematic review and meta-analysis of randomized controlled trials.Archives of gynecology and obstetrics · 2024Pooled it
- The Effects of Throat Packing and Gender on Postoperative Nausea, Vomiting, and Sore Throat in Septorhinoplasty Patients: A Randomized Controlled Trial.Aesthetic plastic surgery · 2026Trial
- Article
- Assessment of nausea across pregnancy and its association with maternal psychological status and perinatal outcomes: a prospective observational study in pregnant women.Scientific reports · 2026Observational
- Transient changes in body weight and behavior during the placentation period in non-human primates and rodents.Scientific reports · 2026Article
- Association between PUQE-based severity of hyperemesis gravidarum and systemic inflammatory indices.BMC pregnancy and childbirth · 2026Article
- Effectiveness of olanzapine for hyperemesis gravidarum in individuals without a psychiatric history: a case report.BMC pregnancy and childbirth · 2026Article
- Nausea and Vomiting in Pregnancy: Prevalence, Clinical Characteristics, and Management Findings from a Prospective Italian Multicenter Cohort Study.Life (Basel, Switzerland) · 2026Article
- Clinical Presentation and Treatment of Hyperemesis Gravidarum in a Lady Carrying Twins in the First Trimester: A Case Reports.Clinical case reports · 2026Article
- Article
- The Serum Platelet-Albumin Ratio in Hyperemesis Gravidarum: A Retrospective Comparative Study.International journal of women's health · 2026Article
- Construction of a Risk Identification Model Based on Electrolytes and Related Factors for Nausea and Vomiting in Pregnancy: A Secondary Analysis of Clinical Trial Data.International journal of women's health · 2026Article
- Gut and Gastric Dysbiosis in Hyperemesis Gravidarum: A Scoping Review of Microbiome-Targeted Evidence and Translational Pathways.International journal of women's health · 2026Review
- Liver function disorders in pregnancy: physiology or pathology?Przeglad gastroenterologiczny · 2026Review
- Evaluation of zonulin levels in pregnant women with hyperemesis gravidarum.BMC pregnancy and childbirth · 2025Article
- Association between nausea and vomiting during pregnancy and adverse pregnancy outcomes: findings from the nuMoM2b study.Archives of gynecology and obstetrics · 2025Article
- Associations of Nausea and Vomiting of Pregnancy with Maternal and Fetal Outcomes.Journal of clinical medicine · 2025Article
- The association between gestational diabetes mellitus and cancer in women: an updated systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nausea and vomiting of pregnancy (NVP) is a common condition that affects up to 70% of pregnant women. Hyperemesis gravidarum (HG) is considered the serious form of NVP, which is reported in 0.3-10.8% of pregnant women. NVP has a relatively benign course, but HG can be linked with some poor maternal, fetal, and offspring outcomes. The exact causes of NVP and HG are unknown, but various factors have been hypothesized to be associated with pathogenesis. With the advance of precision medicine and molecular biology, some genetic factors such as growth/differentiation factor 15 (GDF15) have become therapeutic targets. In our review, we summarize the historical hypotheses of the pathogenesis of NVP and HG including hormonal factors,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.