Evidence map›Paper›PMID 35083129›Full record

ArticleVeterinary medicine (Auckland, N.Z.)2022

Comparative Immunogenicity Evaluation of Two Infectious Bursal Disease Vaccines Commonly Used in Broiler Chickens in Ethiopia.

Likelesh Legese, Berhane Wakjira, Tsedale Teshome, Dereje Nigussie Woldemichael, Hika Waktole, Fikru Regassa, Takele Beyene Tufa

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Likelesh LegeseAddis Ababa University, College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Berhane WakjiraAddis Ababa University, College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Tsedale TeshomeAddis Ababa University, College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Dereje Nigussie WoldemichaelEthiopian Public Health Institute, Vaccine and Diagnostic Production Research, Addis Ababa, Ethiopia.ORCID 0000-0002-2145-5990
Hika WaktoleAddis Ababa University, College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Fikru RegassaAddis Ababa University, College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Takele Beyene TufaAddis Ababa University, College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.ORCID 0000-0003-0383-218X
Addis Ababa University · ETEthiopian Public Health Institute · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInfectious bursal disease (IBD) is one of the most endemic diseases of commercial poultry in Ethiopia. Vaccination is used as the major means of IBD prevention and control. A study was conducted to compare the immunogenicity of two commercially available IBD vaccines in broiler chicken with maternally derived antibody (MDA).

methodsA total of 270 day-one-old chicks were randomly assigned to three groups, group 1 vaccinated with product A vaccine at the age of 7 and 19 days and group 2 with product B vaccine on day 15 and 22 while group 3 were kept as control. Six chickens were also randomly selected and bled on day 1 for differential leukocyte count (DLC) and determination of MDA. Representative chickens from each group were bled at 24th and 42nd days of age for antibody titration using the indirect ELISA test. DLC scores were determined in the 1st and 24th days.

resultsThe result revealed highly significant differences (

conclusionBoth vaccines have induced an adequate immunological response at the end of the experiment; however, product A has shown significantly higher antibody titers against the IBDV and DLC than product B.

Indexed as

antibody titerbroiler chickenIBD vaccinesimmunogenicity evaluation

Identifiers

PMID35083129
PMCPMC8784269
OpenAlexW4205514621

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.