Evidence map›Paper›PMID 35083118›Full record

ArticleJournal of the Saudi Heart Association2021

Predictors of 6-month Mortality in Patients with Non-ST Elevation Acute Coronary Syndrome: A Study in Pakistani Population.

Dileep Kumar, Tahir Saghir, Rajesh Kumar, Jawaid Akbar Sial, Kamran Ahmed Khan, Jehangir Ali Shah, Musa Karim, Abdul Mueed, Reeta Bai, Hitesh Kumar and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of the Saudi Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Dileep KumarDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Tahir SaghirDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Rajesh KumarDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Jawaid Akbar SialDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Kamran Ahmed KhanDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Jehangir Ali ShahDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Musa KarimDepartment of Research, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Abdul MueedDepartment of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan.
Reeta BaiDepartment of Radiology, Dow University of Health Sciences, Karachi, Pakistan.
Hitesh KumarDepartment of Medicine, Government of Sindh, Karachi, Pakistan.
Sajjad AliDepartment of Medicine, Ziauddin Medical University, Karachi, Pakistan.
Rekha KumariDepartment of Medicine, Government of Sindh, Karachi, Pakistan.
National Institute of Cardiovascular Diseases · PKGovernment of Pakistan · PKDow University of Health Sciences · PKZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFor Southern Asian countries like Pakistan, there is inadequate evidence of risk factors associated with mortality in patients suffering from acute coronary syndrome (ACS), especially non-ST elevation ACS (NSTE-ACS) cases. Therefore, aim of this study was to evaluate predictors of 6-months mortality of patients presenting with NSTE-ACS.

methodsFor this prospective observational study we recruited adult patients diagnosed with NSTE-ACS at a tertiary cardiac center. All he patients were followed-up after six months and survival status was recorded. Logistic regression analysis was performed for six-month mortality and odds ratio (OR) and 95% confidence interval (CI) were reported.

resultsSix-month follow-up was successful for 280 patients. On univariate analysis age >65 years, increased heart rate, cardiac arrest at presentation, Killip class II-IV at presentation, and diabetes were found to be associated with increased risk of 6-months mortality with OR [95% CI] of 4.27 [1.9-9.58], 1.25 [1.1-1.41], 139.44 [16.9-1150.78], 68.45 [7.88-594.41], and 2.35 [1.06-5.22] respectively. On multivariable analysis Killip class II-IV at presentation, thrombolysis in myocardial infarction (TIMI) score of >4, and global registry of acute coronary events (GRACE) score ≥150 were found to be independent predictors of mortality after six months of NSTE-ACS with adjusted OR of 32.93 [2.65-408.8], 3.42 [1.35-8.66], and 8.43 [3.33-21.38] respectively.

conclusionsFor patients with NSTE-ACS, our study showed seven clinical parameters to be associated with an increased risk of 6-month mortality. These included increasing age, increased heart rate, cardiac arrest at presentation, Killip class II-IV, diabetes, TIMI score of >4 and GRACE score of >150. Thereby aiding clinicians to apply strategic and precise interventions in monitoring these patients accordingly.

Indexed as

6-month mortalityAcute coronary syndromeNon-ST elevation ACSPredictors

Identifiers

PMID35083118
PMCPMC8754448
OpenAlexW3208730575

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.