Evidence map›Paper›PMID 35083113›Full record

ArticleAnalytical cellular pathology (Amsterdam)2022

Prognostic Role of Tumor Microenvironment in DLBCL and Relation to Patients' Clinical Outcome: A Clinical and Immunohistochemical Study.

Doaa Shams-Deen Ghorab, Ahmed Mohamed Helaly, Hoda Saleh El Mahdi, Moawiah Khatatbeh, Afaf Taha Ibrahiem

Abstract read
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Doaa Shams-Deen GhorabPathology Department, Faculty of Medicine Mansoura University, Egypt.
Ahmed Mohamed HelalyForensic and Clinical Toxicology Department, Mansoura University, Egypt.ORCID https://orcid.org/0000-0003-2510-7229
Hoda Saleh El MahdiPathology Department, Faculty of Medicine Mansoura University, Egypt.
Moawiah KhatatbehBasic Department, Faculty of Medicine Yarmouk University, Jordan.
Afaf Taha IbrahiemPathology Department, Faculty of Medicine Mansoura University, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B cell lymphoma is the most common type of lymphoma in Egypt with an unfavorable prognosis. The tumor microenvironment is rich in immune response either T cells or macrophages. The current study is aimed at testing CD4, CD8, CD68, and MMP9 immunohistochemistry of DLBCL activities with the prognosis of the tumor. The results showed no positive relation between T cell and macrophage reaction to the tumor prognosis suggesting that this reaction is part of the tumor process and not a defense mechanism from the surrounding stroma.

Indexed as

Lymphoma, Large B-Cell, DiffuseTumor MicroenvironmentHumansMacrophagesPrognosisT-Lymphocytes

Identifiers

PMID35083113
PMCPMC8786528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.