Trial reportPain research & management2022
The Effect of Breathing Exercise Using Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 7 to 10 Years: A Crossover Randomized Clinical Trial.
Trial report in Pain research & management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05899452 (Bubble Blowing As an Effective Method for Distraction During Pediatric IV Insertion), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bubble Blowing As an Effective Method for Distraction During Pediatric IV Insertion: a Randomized Controlled Trial
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Non-pharmacological and physical strategies for managing dental anxiety: a systematic review with implications for dental education.Public health reviews · 2026Pooled it
- Clinical effectiveness of diaphragmatic breathing for dental anxiety in 7- to 13-year-old children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Trial
- Comparative efficacy of virtual reality headset and auditory distraction for reducing anxiety and pain during inferior alveolar nerve block in 7-10-year-old children: a clinical trial.BMC pediatrics · 2025Trial
- The Effectiveness of Bubble-Blowing as a Distraction Technique During Pediatric Intravenous Cannulation: A Randomized Controlled Trial.Paediatric anaesthesia · 2025Trial
- Laser acupuncture and photobiomodulation therapy in Bell's palsy with a duration of greater than 8 weeks: a randomized controlled trial.Lasers in medical science · 2024Trial
- Evaluating the Effect of Breathing Exercise Using a Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 6-10 Years: A Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2026Article
- Effect of Hoberman Sphere on Behavior, Anxiety, and Pain in Children during Buccal Infiltration Anesthesia: A Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2025Article
- Effect of Self-designed Game Hop-A-Dent on 6-10-year-old Children's Anxiety Compared with the Tell-Show-Do Method: A Clinical Trial.International journal of clinical pediatric dentistry · 2025Article
- Analyzing Nonpharmacological Behavior Management in Children With Dental Anxiety: A Systematic Review and Meta-Analysis.Health science reports · 2025Review
- Feasibility of Tell-Play-Do Intervention in Outreach Programs: A Group-based Behavior Management Approach for Anxiety Reduction.International journal of clinical pediatric dentistry · 2025Article
- Exploring Novel Behavior Modification Techniques-Comparing the Effectiveness of Bach Flower Therapy and Bubble Breath Play Therapy on Dental Anxiety in Pediatric Patients: A Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2025Article
- Respiratory muscle training reduces painful swallowing and opioid use during radiation therapy for head and neck cancer: a matched pair analysis.BMC cancer · 2025Article
- The Effect of Diaphragmatic Breathing as a Complementary Therapeutic Strategy in Stress of Children and Teenagers 6-18 Years Old.Children (Basel, Switzerland) · 2025Review
- Comparison of the Efficacy of Aromatherapy and Bubble Breath Play Therapy in Reducing Dental Anxiety in Children: A Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2025Article
- Thaumaturgical Distraction as a Modality for Reducing Dental Anxiety in Children: A Systematic Review.International journal of clinical pediatric dentistry · 2024Article
- Strategies for Managing Pediatric Fracture Pain: Assessment, Pharmacological, and Non-Pharmacological Interventions.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Special Characteristics of Alpha Generation Children Behavior in Dentistry: A Literature Review.European journal of dentistry · 2024Article
- Effectiveness of Nonpharmacological Behavioural Interventions in Managing Dental Fear and Anxiety among Children: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2024Review
- Efficacy of Virtual Reality Distraction in Reduction of Pain and Anxiety of Pediatric Dental Patients in an Iranian Population: A Split-Mouth Randomized Crossover Clinical Trial.International journal of dentistry · 2024Article
- Assessment of Different Distraction Behavioral Methods in Pediatric Dental Clinic: A Systematic Review.Cureus · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to evaluate the effect of breathing exercise using bubble blower on anxiety and pain during inferior alveolar nerve block (IANB) in children aged 7 to 10 years. MATERIALS AND
methodsIn this randomized crossover clinical trial, thirty-five children with moderate to severe anxiety requiring bilateral pulp therapy of mandibular primary molars were enrolled. Based on random lists, 18 children received the BE + IANB and 17 children received a routine IANB at the first session. This trend became reverse at the second visit for each child. Anxiety was measured using Facial Image Scale (FIS), blood pressure, and pulse rate. Face Leg Activity Cry Consolability (FLACC) scale and Wong-Baker Facial Pain Scale (WBFPS) were used for pain measurement. The Paired Samples Test, Wilcoxon Signed Rank Test, and Interclass Correlation Coefficient were used for data analysis.
resultsThe means of FLACC, WBFPS, FIS, blood pressure, and pulse rate were higher at the control visit. However, these differences were statistically significant only for FLACC scale and WBFPS (
conclusionBreathing exercise using a bubble blower may be an efficient distraction and relaxation method to decrease pain of 7- to 10-year-old children with moderate to severe anxiety during inferior alveolar nerve block. However, anxiety levels were lower when applying BE, and the differences were not statistically significant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.