Evidence map›Paper›PMID 35082933›Full record

ArticleDisease markers2022

Analysis of Macular Retinal Thickness and Microvascular System Changes in Children with Monocular Hyperopic Anisometropia and Severe Amblyopia.

Lin-Lin Liu, Yu-Chuan Wang, Miao Cao, Fang Liu, Shuang Zhang, Jing Liu, Jin-Chang Liu, Lian-Feng Xie, Hui Wang

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Reduced Retinal Vascular Density and Skeleton Length in Amblyopia.Translational vision science & technology · 2024
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lin-Lin LiuThe Department of Ophthalmology of the 1st Affiliated Hospital, Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.ORCID https://orcid.org/0000-0001-8282-5863
Yu-Chuan WangPostgraduates at Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Miao CaoPostgraduates at Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Fang LiuPostgraduates at Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Shuang ZhangThe Department of Ophthalmology of the 1st Affiliated Hospital, Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Jing LiuThe Department of Ophthalmology of the 1st Affiliated Hospital, Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Jin-Chang LiuThe Department of Ophthalmology of the 1st Affiliated Hospital, Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Lian-Feng XieThe Department of Ophthalmology of the 1st Affiliated Hospital, Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Hui WangThe Department of Ophthalmology of the 1st Affiliated Hospital, Gannan Medical University, Ganzhou, 341000 Jiangxi Province, China.
Gannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the changes of macular retinal thickness and microvascular system in children with monocular hyperopic anisometropia and severe amblyopia using optical coherence tomography angiography (OCTA) and to explore the value of OCTA in the diagnosis and treatment of amblyopia.

methodsThirty-two children with monocular hyperopic anisometropia and severe amblyopia who were treated in the Department of Ophthalmology of the First Affiliated Hospital of Gannan Medical College from January 2020 to December 2020 were included in the study. Eyes with amblyopia (

resultsThe vessel densities of macular SCP in the amblyopia and control groups were 47.66 ± 2.36% and 50.37 ± 2.24% in the outer superior, 49.19 ± 2.64% and 51.44 ± 2.44% in the inner inferior, 49.63 ± 2.51% and 51.41 ± 3.03% in the outer inferior, and 45.56 ± 3.44% and 50.44 ± 3.52% in the outer temporal regions, respectively. The vessel density of macular SCP in the amblyopia group was significantly lower than that in contralateral healthy eyes in the outer superior, inner inferior, outer inferior, outer temporal, and central regions. There was no significant difference between the two groups in the inner superior, inner nasal, outer nasal, and inner temporal regions. The macular RT in the amblyopia group and the control group is 90.38 ± 6.09

conclusionThe OCTA results showed the overall RT of macula in 9 areas in the amblyopia group was thicker than that in the control group, which could show that the macular retinal thickness can be a potential way to distinguish the children with monocular hyperopic anisometropia and severe amblyopia.

Indexed as

AmblyopiaAnisometropiaCase-Control StudiesChildCross-Sectional StudiesFemaleHumansMacula LuteaMaleTomography, Optical CoherenceVisual Acuity

Identifiers

PMID35082933
PMCPMC8786532
OpenAlexW4205598553

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.