ArticleDisease markers2022
Decreased Adiponectin Levels Are a Risk Factor for Cognitive Decline in Spinal Cord Injury.
Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Review
- Cognitive assessment during inpatient rehabilitation after spinal cord injury, a retrospective cross-sectional study.Spinal cord · 2024Article
- Adiponectin in spinal cord injury: What is the role of nutrition in serum adiponectin concentration?Turkish journal of physical medicine and rehabilitation · 2024Article
- Serum neutrophil gelatinase-associated lipocalin as a potential biomarker for cognitive decline in spinal cord injury.Frontiers in neurology · 2023Article
- Higher serum β2-microglobulin is a predictive biomarker for cognitive impairment in spinal cord injury.PeerJ · 2023Article
- Netrin-1: A Serum Marker Predicting Cognitive Impairment after Spinal Cord Injury.Disease markers · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSpinal cord injury (SCI) has become popular in recent years, and cognitive decline is a common complication. Adiponectin is a common protein hormone involved in the course of many diseases, but its relationship with SCI has not yet been elucidated. The purpose of our prospective study is to explore whether adiponectin can be used as a biomarker of cognitive decline in SCI.
methodsA total of 64 healthy volunteers and 92 patients with acute SCI were recruited by us. Serum adiponectin levels, demographic data (age and gender), lifestyle (smoking and drinking), medical history (diabetes and hypertension), and clinical baseline data (low-density lipoprotein, high-density lipoprotein, and fasting blood glucose) were recorded. Three months after enrollment, we used the Montreal Cognitive Assessment (MoCA) to evaluate cognitive function. Based on a quarter of the serum adiponectin levels, SCI patients were divided into 4 groups, and the differences in their MoCA scores were compared. In addition, we used multivariate linear regression to predict the risk factors of the MoCA score.
resultsThe serum adiponectin level (6.1 ± 1.1
conclusionsSerum adiponectin levels can be used as an independent predictor of cognitive function in patients with acute SCI.
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Registered trials
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