SynthesisFrontiers in endocrinology2021
Association Between Prediabetes and Erectile Dysfunction: A Meta-Analysis.
Synthesis in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic syndrome and erectile dysfunction: a systematic review and meta-analysis study.Journal of endocrinological investigation · 2023Pooled it
- Prevalence and predictors of erectile dysfunction among men in the diabetes prevention program outcomes study.Journal of diabetes and its complications · 2024Trial
- Glucagon-like receptor-1 agonists and impotence: A meta-analysis.World journal of methodology · 2026Article
- Penile Hemodynamic Patterns Highlighting the Impact of Diabetes in Young Men With Erectile Dysfunction.Andrology · 2026Article
- Dysglycemia and Cardiometabolic Risk: Pathophysiological Rationale and the Emerging Role of Nutraceuticals in Integrated Prevention.Nutrients · 2026Review
- Steps to construct educational interventions on sexual dysfunction for healthcare professionals and patients. Experiences from the SECRET research study-group.PEC innovation · 2024Article
- Rapid Lifestyle Recommendations to Improve Urologic, Heart and Overall Health.Current urology reports · 2024Review
- Association between erectile dysfunction and the prevalence and prognosis of hyperglycemia in adults in the USA based on NHANES 2001-2004.Scientific reports · 2024Article
- Assessment of Hypogonadism and Erectile Dysfunction in Males with Prediabetes: A Cross-Sectional Study from North India.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Diabetes has been associated with the increased risk of erectile dysfunction (ED). However, previous studies evaluating the association between prediabetes and ED showed inconsistent results. We performed a meta-analysis of observational studies to systematically evaluate the above association. Methods: Relevant observational studies were retrieved by search of PubMed, Embase, and Web of Science databases. A random-effect model which incorporated the potential intra-study heterogeneity was used for the meta-analysis. Subgroup analyses were performed to evaluate the influences of study characteristics on the outcome. Results: Nine studies (five matched case-control studies and four cross-sectional studies) were included. Age were adjusted or matched in all of the studies. Pooled results showed that compared to men with normoglycemia, men with prediabetes were associated with higher prevalence of ED (odds ratio = 1.62, 95% confidence interval: 1.28 to 2.07, P < 0.001; I Conclusions: Prediabetes is associated with higher prevalence of ED, which may be independent of age of the males and may be stronger in young men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.