Evidence map›Paper›PMID 35082501›Full record

ArticleJournal of asthma and allergy2022

Exercise Limitation in Children and Adolescents with Mild-to-Moderate Asthma.

Olga Lagiou, Sotirios Fouzas, Dimosthenis Lykouras, Xenophon Sinopidis, Ageliki Karatza, Kiriakos Karkoulias, Gabriel Dimitriou, Michael B Anthracopoulos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Olga Lagiou *Pediatric Respiratory Unit, University of Patras Medical School, Patras, Greece.
Sotirios Fouzas *Pediatric Respiratory Unit, University of Patras Medical School, Patras, Greece.
Dimosthenis LykourasDepartment of Respiratory Medicine, University Hospital of Patras, Patras, Greece.
Xenophon SinopidisDepartment of Pediatrics, University of Patras Medical School, Patras, Greece.
Ageliki KaratzaDepartment of Pediatrics, University of Patras Medical School, Patras, Greece.
Kiriakos KarkouliasDepartment of Respiratory Medicine, University Hospital of Patras, Patras, Greece.
Gabriel DimitriouDepartment of Pediatrics, University of Patras Medical School, Patras, Greece.
Michael B AnthracopoulosPediatric Respiratory Unit, University of Patras Medical School, Patras, Greece.
University of Patras · GRGeneral University Hospital of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with uncontrolled asthma are less tolerant to exercise due to ventilatory limitation, exercise-induced bronchoconstriction (EIB), or physical deconditioning. The contribution of these factors in children with controlled mild-to-moderate asthma is unknown.

objectiveTo explore the underlying mechanisms of reduced exercise capacity in children with controlled mild-to-moderate asthma.

methodsThis was a cross-sectional study of 45 children and adolescents (age 8-18 years) with controlled mild-to-moderate asthma (asthma control test score 21-25) and 61 age-matched healthy controls. All participants completed a physical activity questionnaire and performed spirometry and cardiopulmonary exercise testing (CPET; maximal incremental protocol). Spirometric indices and CPET parameters were compared between the two groups. The effect of EIB (FEV

results62.2% of children with asthma and 29.5% of controls (P = 0.002) were categorized as inactive. Reduced exercise capacity (O

conclusionChildren with controlled mild-to-moderate asthma are less tolerant to strenuous exercise than their healthy peers. The decreased exercise capacity in this population should mainly be attributed to physical deconditioning, while the contribution of ventilatory limitation and EIB is rather small.

Indexed as

asthmacardiopulmonary exercise testingchildrenexercise

Identifiers

PMID35082501
PMCPMC8785132
OpenAlexW4205130464

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.