Evidence map›Paper›PMID 35082355›Full record

ArticleScientific reports2022

Automated retinal boundary segmentation of optical coherence tomography images using an improved Canny operator.

Jian Liu, Shixin Yan, Nan Lu, Dongni Yang, Hongyu Lv, Shuanglian Wang, Xin Zhu, Yuqian Zhao, Yi Wang, Zhenhe Ma and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jian LiuSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China.
Shixin YanSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China.
Nan LuDepartment of Ophthalmology, The First Hospital of Qinhuangdao, Qinhuangdao, 066004, China.
Dongni YangDepartment of Ophthalmology, The First Hospital of Qinhuangdao, Qinhuangdao, 066004, China.
Hongyu LvDepartment of Ophthalmology, Qinhuangdao Maternal and Child Health Hospital, Qinhuangdao, 066004, China.
Shuanglian WangTangshan Maternal and Children Hospital, Tang shan, 063000, China.
Xin ZhuBiomedical Information Engineering Lab, The University of Aizu, Aizu-Wakamatsu, Fukushima, 9650053, Japan.
Yuqian ZhaoSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China.
Yi WangSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China.
Zhenhe MaSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China.
Yao YuSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China. y.j.yu@outlook.com.

Funding

National Natural Science Foundation of China 61771119National Natural Science Foundation of China 61901100National Natural Science Foundation of China 62075037Natural Science Foundation of Hebei Province E2020501029Natural Science Foundation of Hebei Province F2019501132Natural Science Foundation of Hebei Province F2020501040Natural Science Foundation of Hebei Province H2019501010
6 · The paper itself

Abstract

Retinal segmentation is a prerequisite for quantifying retinal structural features and diagnosing related ophthalmic diseases. Canny operator is recognized as the best boundary detection operator so far, and is often used to obtain the initial boundary of the retina in retinal segmentation. However, the traditional Canny operator is susceptible to vascular shadows, vitreous artifacts, or noise interference in retinal segmentation, causing serious misdetection or missed detection. This paper proposed an improved Canny operator for automatic segmentation of retinal boundaries. The improved algorithm solves the problems of the traditional Canny operator by adding a multi-point boundary search step on the basis of the original method, and adjusts the convolution kernel. The algorithm was used to segment the retinal images of healthy subjects and age-related macular degeneration (AMD) patients; eleven retinal boundaries were identified and compared with the results of manual segmentation by the ophthalmologists. The average difference between the automatic and manual methods is: 2-6 microns (1-2 pixels) for healthy subjects and 3-10 microns (1-3 pixels) for AMD patients. Qualitative method is also used to verify the accuracy and stability of the algorithm. The percentage of "perfect segmentation" and "good segmentation" is 98% in healthy subjects and 94% in AMD patients. This algorithm can be used alone or in combination with other methods as an initial boundary detection algorithm. It is easy to understand and improve, and may become a useful tool for analyzing and diagnosing eye diseases.

Indexed as

AlgorithmsArtifactsFemaleHumansMacular DegenerationMiddle AgedRetinaTomography, Optical Coherence

Identifiers

PMID35082355
PMCPMC8791938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.