Evidence map›Paper›PMID 35082319›Full record

ArticleScientific reports2022

Arousal-based pupil modulation is dictated by luminance.

Jasmine Pan, Michaela Klímová, Joseph T McGuire, Sam Ling

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Modality-general sensitivity of pupil responses to regularity violations.Cognitive, affective & behavioral neuroscience · 2026
    Article
  2. Task-Evoked Pupillary Dynamics Are Altered in Post-COVID Syndrome.Medical sciences (Basel, Switzerland) · 2026
    Article
  3. Heterogeneous Effects of Cognitive Arousal on the Contrast Response in Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jasmine PanPsychological and Brain Sciences, Boston University, Boston, MA, USA. jasminep@bu.edu.
Michaela KlímováPsychological and Brain Sciences, Boston University, Boston, MA, USA.
Joseph T McGuirePsychological and Brain Sciences, Boston University, Boston, MA, USA.
Sam LingPsychological and Brain Sciences, Boston University, Boston, MA, USA.

Funding

How Does Normalization Regulate Visual Competition?R01EY028163 · NEI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SAM LING · 2017 to 2026
$3.7M
Where orientation selectivity arises, and how it can changeF32EY019802 · NEI · VANDERBILT UNIVERSITY · PI LING, SAM · 2009 to 2009
$50k
NEI NIH HHS F32 EY019802NEI NIH HHS R01 EY028163
6 · The paper itself

Abstract

Pupillometry has become a standard measure for assessing arousal state. However, environmental factors such as luminance, a primary dictator of pupillary responses, often vary across studies. To what degree does luminance interact with arousal-driven pupillary changes? Here, we parametrically assessed luminance-driven pupillary responses across a wide-range of luminances, while concurrently manipulating cognitive arousal using auditory math problems of varying difficulty. At the group-level, our results revealed that the modulatory effect of cognitive arousal on pupil size interacts multiplicatively with luminance, with the largest effects occurring at low and mid-luminances. However, at the level of individuals, there were qualitatively distinct individual differences in the modulatory effect of cognitive arousal on luminance-driven pupillary responses. Our findings suggest that pupillometry as a measure for assessing arousal requires more careful consideration: there are ranges of luminance levels that are more ideal in observing pupillary differences between arousal conditions than others.

Indexed as

LightAcoustic StimulationAdolescentAdultArousalCognitionFemaleFixation, OcularHeart RateHumansMalePhotic StimulationPupilScreen TimeVision, OcularYoung Adult

Identifiers

PMID35082319
PMCPMC8792027

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.