ArticleScientific reports2022
Risk of Plasmodium falciparum infection in south-west Burkina Faso: potential impact of expanding eligibility for seasonal malaria chemoprevention.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Associations Between Climate-Sensitive Nutrients, Clinical Malaria, and Anaemia Among Young Children in Rural Burkina Faso: An Analysis of Baseline Data From a Cluster-Randomised Controlled Trial.Tropical medicine & international health : TM & IH · 2026Trial
- Evaluating artesunate monotherapy and dihydroartemisinin-piperaquine as potential antimalarial options for prevaccination radical cures during future malaria vaccine field efficacy trials.Malaria journal · 2024Trial
- Safety and immunogenicity of BK-SE36 in a blinded, randomized, controlled, age de-escalating phase Ib clinical trial in Burkinabe children.Frontiers in immunology · 2022Trial
- Changing Species Dynamics and Species-Specific Associations Observed between Anopheles and Plasmodium Genera in Diebougou Health District, Southwest Burkina Faso.The American journal of tropical medicine and hygiene · 2026Article
- Malaria prevalence and epidemiological characteristics in Northern Malawi: a nine-year retrospective hospital-based study.Malaria journal · 2026Article
- Malaria among febrile patients during a yellow fever outbreak in Ghana: a cross-sectional study.Malaria journal · 2026Article
- Funded investments contributed to the reduction of malaria morbidity and mortality in children under five: fifteen years retrospective study from 2009 to 2023 in Burkina Faso.Malaria journal · 2026Article
- Co-occurrence of anaemia and malaria among children under five in Uganda: A joint modeling analysis.PLOS global public health · 2026Article
- Testing the feasibility and utility of an executive function battery for use with primary school-aged students in Malawi.PLOS global public health · 2025Article
- Article
- Circulation of non-falciparum malaria species in West Africa: A literature review from 2000 to 2024.MalariaWorld journal · 2025Review
- Impact of Climate Variability and Interventions on Malaria Incidence and Forecasting in Burkina Faso.International journal of environmental research and public health · 2024Article
- Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile.Malaria journal · 2024Review
- Current Status of Malaria Control and Elimination in Africa: Epidemiology, Diagnosis, Treatment, Progress and Challenges.Journal of epidemiology and global health · 2024Review
- Mature beyond their years: young children who escape detection of parasitemia despite living in settings of intense malaria transmission.Biochemical Society transactions · 2024Review
- Relative effects of climate factors and malaria control interventions on changes of parasitaemia risk in Burkina Faso from 2014 to 2017/2018.BMC infectious diseases · 2024Article
- Malaria prevalence and use of control measures in an area with persistent transmission in Senegal.PloS one · 2024Article
- Seasonal malaria chemoprevention in a context of high presumed sulfadoxine-pyrimethamine resistance: malaria morbidity and molecular drug resistance profiles in South Sudan.Malaria journal · 2023Article
- Malariometric Indices in the Context of Seasonal Malaria Chemoprevention in Children Aged 1.5 to 12 Years during the Period of High Malaria Transmission in the Suburban Area of Banfora, Burkina Faso.Tropical medicine and infectious disease · 2023Article
- Seasonal malaria chemoprevention in Africa and China's upgraded role as a contributor: a scoping review.Infectious diseases of poverty · 2023Article
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Authors and funding
17 authors at 5 institutions in 2 countries.
Funding
Abstract
Burkina Faso has one of the highest malaria burdens in sub-Saharan Africa despite the mass deployment of insecticide-treated nets (ITNs) and use of seasonal malaria chemoprevention (SMC) in children aged up to 5 years. Identification of risk factors for Plasmodium falciparum infection in rural Burkina Faso could help to identify and target malaria control measures. A cross-sectional survey of 1,199 children and adults was conducted during the peak malaria transmission season in the Cascades Region of south-west Burkina Faso in 2017. Logistic regression was used to identify risk factors for microscopically confirmed P. falciparum infection. A malaria transmission dynamic model was used to determine the impact on malaria cases averted of administering SMC to children aged 5-15 year old. P. falciparum prevalence was 32.8% in the study population. Children aged 5 to < 10 years old were at 3.74 times the odds (95% CI = 2.68-5.22, P < 0.001) and children aged 10 to 15 years old at 3.14 times the odds (95% CI = 1.20-8.21, P = 0.02) of P. falciparum infection compared to children aged less than 5 years old. Administration of SMC to children aged up to 10 years is predicted to avert an additional 57 malaria cases per 1000 population per year (9.4% reduction) and administration to children aged up to 15 years would avert an additional 89 malaria cases per 1000 population per year (14.6% reduction) in the Cascades Region, assuming current coverage of pyrethroid-piperonyl butoxide ITNs. Malaria infections were high in all age strata, although highest in children aged 5 to 15 years, despite roll out of core malaria control interventions. Given the burden of infection in school-age children, extension of the eligibility criteria for SMC could help reduce the burden of malaria in Burkina Faso and other countries in the region.
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