Evidence map›Paper›PMID 35082153›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

A widely distributed phosphate-insensitive phosphatase presents a route for rapid organophosphorus remineralization in the biosphere.

Ian D E A Lidbury, David J Scanlan, Andrew R J Murphy, Joseph A Christie-Oleza, Maria M Aguilo-Ferretjans, Andrew Hitchcock, Tim J Daniell

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 101 citations in OpenAlex.

  1. Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
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  8. Widespread promiscuous alkaline phosphatases underscore ancient microbial phosphite utilization.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
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  11. Methionine synthesis and glycine betaine demethylation are intricately intertwined in cosmopolitan marine bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. The microbial phosphorus cycle in aquatic ecosystems.Nature reviews. Microbiology · 2025
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ian D E A LidburyPlants, Photosynthesis and Soil, School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom; i.lidbury@sheffield.ac.uk.ORCID 0000-0001-7190-315X
David J ScanlanSchool of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.ORCID 0000-0003-3093-4245
Andrew R J MurphySchool of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.ORCID 0000-0001-6586-2363
Joseph A Christie-OlezaDepartment of Biology, University of the Balearic Islands, Palma 07122, Spain.
Maria M Aguilo-FerretjansDepartment of Biology, University of the Balearic Islands, Palma 07122, Spain.ORCID 0000-0001-8455-7153
Andrew HitchcockPlants, Photosynthesis and Soil, School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.ORCID 0000-0001-6572-434X
Tim J DaniellPlants, Photosynthesis and Soil, School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.ORCID 0000-0003-0435-4343
University of Sheffield · GBUniversitat de les Illes Balears · ESUniversity of Warwick · GB

Funding

Biotechnology and Biological Sciences Research Council BB/T009152/1
6 · The paper itself

Abstract

The regeneration of bioavailable phosphate from immobilized organophosphorus represents a key process in the global phosphorus cycle and is facilitated by enzymes known as phosphatases. Most bacteria possess at least one of three phosphatases with broad substrate specificity, known as PhoA, PhoX, and PhoD, whose activity is optimal under alkaline conditions. The production and activity of these phosphatases is repressed by phosphate availability. Therefore, they are only fully functional when bacteria experience phosphorus-limiting growth conditions. Here, we reveal a previously overlooked phosphate-insensitive phosphatase, PafA, prevalent in

Indexed as

Bacterial ProteinsBacteroidetesBiodiversityFlavobacteriumPhosphatesPhosphoric Monoester HydrolasesPhosphorusBacterial ProteinsPhosphatesPhosphoric Monoester HydrolasesPhosphorusBacteroidetesflavobacteriaorganic phosphorusPafAphosphatase

Identifiers

PMID35082153
PMCPMC8812569
OpenAlexW4210438382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.