Evidence map›Paper›PMID 35082128›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2022

Current unmet needs and potential solutions to uncontrolled asthma.

William W Busse, Monica Kraft

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06364527 (Use of Aptar Digital Health's Respiratory Disease Management Platform for Asthma), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06364527 nacompletednot on this mapstarted 2024, after this paper: background citation

Use of Aptar Digital Health's Respiratory Disease Management Platform for Asthma: A Pilot Study

TypeinterventionalSponsorCoheroHealthRan2024 to 2026Enrolled94ConditionsAsthma ChronicArmsAptar Digital Health respiratory disease management platform
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Clinical Practice Guideline: Immunotherapy for Inhalant Allergy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Guideline
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  6. Review
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  14. Guideline-based asthma treatment in Asia: Insights from a robust time-in-state model.The journal of allergy and clinical immunology. Global · 2025
    Article
  15. Article
  16. Stock inhalers in action: results of a pilot study across multiple Illinois counties.The Journal of asthma : official journal of the Association for the Care of Asthma · 2025
    Article
  17. Article
  18. Why Every Asthma Patient Tells a Different Story.Journal of clinical medicine · 2025
    Article
  19. Article
  20. Multidisciplinary care in pediatric severe asthma: A comparative outcomes analysis.The journal of allergy and clinical immunology. Global · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

William W BusseDept of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA wwb@medicine.wisc.edu.
Monica KraftUniversity of Arizona College of Medicine, Tucson, AZ, USA.
University of Arizona · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the availability of effective inhaled therapies, many patients with asthma have poor asthma control. Uncontrolled asthma presents a significant burden on the patient and society, and, for many, remains largely preventable. There are numerous reasons why a patient may remain uncontrolled despite access to therapies, including incorrect inhaler technique, poor adherence to treatment, oversight of triggers and suboptimal medical care. Shared decision-making, good patient-clinician communication, supported self-management, multidisciplinary patient education, new technology and risk stratification may all provide solutions to this major unmet need in asthma. Novel treatments such as biologics could benefit patients' lives, while the investigations into biomarkers, non-Type 2 asthma, treatable traits and disease modification give an exciting glimpse into the future of asthma care.

Indexed as

Anti-Asthmatic AgentsAsthmaHumansNebulizers and VaporizersAnti-Asthmatic Agents

Identifiers

PMID35082128
PMCPMC9488919
OpenAlexW4210816811

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.