Evidence map›Paper›PMID 35081984›Full record

ArticleThe international journal of behavioral nutrition and physical activity2022

'Finishing the race' - a cohort study of weight and blood glucose change among the first 36,000 patients in a large-scale diabetes prevention programme.

Antonia M Marsden, Peter Bower, Elizabeth Howarth, Claudia Soiland-Reyes, Matt Sutton, Sarah Cotterill

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of behavioral nutrition and physical activity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Article
  3. Preventing type 2 diabetes: a qualitative study exploring the complexity of health-related practices in people with prediabetes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Antonia M MarsdenCentre for Biostatistics, School of Health Sciences, University of Manchester, Oxford Road, Manchester, M16 0BY, UK. antonia.marsden@manchester.ac.uk.ORCID 0000-0003-3955-2649
Peter BowerCentre for Primary Care and Health Services Research, NIHR ARC Greater Manchester, School of Health Sciences, University of Manchester, Manchester, UK.
Elizabeth HowarthCentre for Biostatistics, School of Health Sciences, University of Manchester, Oxford Road, Manchester, M16 0BY, UK.
Claudia Soiland-ReyesResearch & Innovation, Northern Care Alliance NHS Group, Manchester, UK.
Matt SuttonCentre for Primary Care and Health Services Research, NIHR ARC Greater Manchester, School of Health Sciences, University of Manchester, Manchester, UK.
Sarah CotterillCentre for Biostatistics, School of Health Sciences, University of Manchester, Oxford Road, Manchester, M16 0BY, UK.
University of Manchester · GBManchester Academic Health Science Centre · GBNorthern Health and Social Care Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe NHS Diabetes Prevention Programme for England, "Healthier You", encourages behaviour change regarding healthy eating and physical exercise among people identified to be at high risk of developing type 2 diabetes. The aim of this research was to examine change, and factors associated with change, in measures of HbA1c and weight in participants and completers of the programme between 2016 and 2019.

methodsParticipant-level data collected by programme service providers on referrals prior to March 2018 was analysed. Changes from baseline to both 6 months and completion in HbA1c and weight were examined using mixed effects linear regression, adjusting for patient characteristics, service provider and site.

resultsCompleters had average improvements in HbA1c of 2.1 mmol/mol [95% CI: - 2.2, - 2.0] (0.19% [95% CI: - 0.20, - 0.18]) and reductions of 3.6 kg [95% CI: - 3.6, - 3.5] in weight, in absolute terms. Variation across the four providers was observed at both time points: two providers had significantly smaller average reductions in HbA1c and one provider had a significantly smaller average reduction in weight compared to the other providers. At both time points, ex- or current smokers had smaller reductions in HbA1c than non-smokers and those from minority ethnic groups lost less weight than White participants. For both outcomes, associations with other factors were small or null and variation across sites remained after adjustment for provider and case mix.

conclusionsParticipants who completed the programme, on average, experienced improvements in weight and HbA1c. There was substantial variation in HbA1c change and smaller variation in weight loss between providers and across different sites. Aside from an association between HbA1c change and smoking, and between weight loss and ethnicity, results were broadly similar regardless of patient characteristics.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2Cohort StudiesGlucoseGlycated HemoglobinHumansWeight LossBlood GlucoseGlucoseGlycated HemoglobinDiabetes preventionHbA1c reductionProgramme evaluationPublic healthWeight loss

Identifiers

PMID35081984
PMCPMC8793225
OpenAlexW4210626813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.