Evidence map›Paper›PMID 35081905›Full record

ArticleBMC public health2022

Association between comorbidity and health-related quality of life in a hypertensive population: a hospital-based study in Bangladesh.

Adnan Mannan, Kazi Mahmuda Akter, Farhana Akter, Naim Uddin Hasan A Chy, Nazmul Alam, Susmita Dey Pinky, Abul Faisal Md Nuruddin Chowdhury, Parijat Biswas, Afrin Sultana Chowdhury, Mohammed Akram Hossain and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

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  13. Socio-demographic disparities in health-related quality of life in hypertensive patients in Bangladesh: a comprehensive survey analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Adnan MannanDepartment of Genetic Engineering & Biotechnology, Faculty of Biological Sciences, University of Chittagong, Chattogram, 4331, Bangladesh. adnan.mannan@cu.ac.bd.
Kazi Mahmuda AkterDepartment of Obstetrics and Gynaecology, Sir Salimullah Medical College Mitford Hospital, Dhaka, 1206, Bangladesh.
Farhana AkterDepartment of Endocrinology, Chittagong Medical College, Chattogram, 4203, Bangladesh.
Naim Uddin Hasan A ChyHealth Economics Research Group, Department of Economics, University of Chittagong, Chattogram, 4331, Bangladesh.
Nazmul AlamDepartment of Public Health, Asian University for Women, Chattogram, 4000, Bangladesh.
Susmita Dey PinkyDepartment of Medicine, Chittagong Medical College, Chattogram, 4203, Bangladesh.
Abul Faisal Md Nuruddin ChowdhuryDepartment of Medicine, Chittagong Medical College, Chattogram, 4203, Bangladesh.
Parijat BiswasDepartment of Medicine, Chittagong Medical College, Chattogram, 4203, Bangladesh.
Afrin Sultana ChowdhuryDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh.
Mohammed Akram HossainDepartment of Cardiology, 250 Bedded General Hospital, Chattogram, 4000, Bangladesh.
Md Mashud RanaDepartment of Pharmacology and Therapeutics, Chittagong Medical College, 4203, Chattogram, Bangladesh.
Chittagong Medical College · BDNoakhali Science and Technology University · BDUniversity of Chittagong · BDAsian University for Women · BDDhaka Medical College and Hospital · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension is a known risk factor for several chronic conditions including diabetes and cardiovascular diseases. However, little is known about its impact on Health-related quality of life (HRQoL) in the context of Bangladesh. This study aimed to evaluate the association of hypertension on HRQoL among Bangladeshi patients corresponding to the socio-demographic condition, comorbid conditions, treatment, and health outcomes.

methodsA hospital based cross-sectional study was conducted using a pre-tested structured questionnaire among patients with hypertension in 22 tertiary medical college hospitals in Bangladesh. The study recruited male and female hypertensive patients of age ≥18 years between July 2020 to February 2021 using consecutive sampling methods. Health related quality of life was measured using the widely-used index of EQ-5D that considers 243 different health-related attributes and uses a scale in which 0 indicates a health state equivalent to death and 1 indicates perfect health status. The five dimensions of the quality index included mobility, self-care, usual activities, pain or discomfort, and anxiety or depression. Ordered logit regression and linear regression models were used to estimate the predictors of comorbidity and HRQoL.

resultsOf the 1,912 hypertensive patients, 56.2% were female, 86.5% were married, 70.7% were either overweight or obese, 67.6% had a family history of hypertension, and 85.5% were on anti-hypertensive medication. Among the individuals with comorbidities, 47.6% had diabetes, 32.3% were obese, 16.2% had heart disease, 15% were visually impaired, and 13.8% were suffering from psychological diseases. HRQoL was found to be inversely proportional to the number of comorbidities. The most frequent comorbidities of diabetes and obesity showed the highest EQ- 5D mean utilities of 0.59 and 0.64, respectively.

conclusionsPrevalent comorbidities, diabetes and obesity were found to be the significant underlying causes of declining HRQoL. It is recommended that the comorbidities should be adequately addressed for better HRQoL. Special attention should be given to address mental health issues of patients with hypertension.

Indexed as

HypertensionQuality of LifeAdolescentBangladeshComorbidityCross-Sectional StudiesFemaleHospitalsHumansMaleObesitySurveys and QuestionnairesBangladeshComorbidityEQ-5D-3LHealth-Related Quality of Life (HRQoL)Hypertension (HTN)

Identifiers

PMID35081905
PMCPMC8793199
OpenAlexW4210334996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.