Evidence map›Paper›PMID 35081744›Full record

ArticleJournal of neurotrauma2022

Brain Injury Effects on Neuronal Activation and Synaptic Transmission in the Basolateral Amygdala of Adult Male and Female Wistar Rats.

Alejandra Jacotte-Simancas, Jason W Middleton, Zachary F Stielper, Scott Edwards, Patricia E Molina, Nicholas W Gilpin

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alejandra Jacotte-SimancasDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Jason W MiddletonDepartment of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Zachary F StielperDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Scott EdwardsDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Patricia E MolinaDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Nicholas W GilpinDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Louisiana State University Health Sciences Center New Orleans · USSoutheast Louisiana Veterans Health Care System · US

Funding

Alcohol and Traumatic Brain Injury; Neuronal and Behavioral ConsequencesR01AA025792 · NIAAA · LSU HEALTH SCIENCES CENTER · PI GILPIN, NICHOLAS WARREN, MOLINA, PATRICIA E. · 2018 to 2022
$1.9M
Targeting Melanocortin-4 Receptors to Reduce Pain in U.S. VeteransI01BX003451 · VA · SOUTHEAST LOUISIANA VETERANS HEALTH CARE · PI GILPIN, NICHOLAS WARREN · 2017 to 2025
–
BLRD VA I01 BX003451NIAAA NIH HHS R01 AA025792
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is defined as brain damage produced by an external mechanical force that leads to behavioral, cognitive, and psychiatric sequelae. The basolateral amygdala (BLA) is involved in emotional regulation, and its function and morphology are altered following TBI. Little is known about potential sex-specific effects of TBI on BLA neuronal function, but it is critical for the field to identify potential sex differences in TBI effects on brain and behavior. Here, we hypothesized that TBI would produce sex-specific acute (1 h) effects on BLA neuronal activation, excitability, and synaptic transmission in adult male and female rats. Forty-nine Wistar rats (

Indexed as

Basolateral Nuclear ComplexBrain InjuriesAnimalsFemaleMaleNeuronsRatsRats, WistarSynaptic Transmissionamygdalaanxietyelectrophysiologylateral fluid percussion

Identifiers

PMID35081744
PMCPMC8978566
OpenAlexW4210517402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.