Evidence map›Paper›PMID 35081668›Full record

ArticleEarly intervention in psychiatry2022

Relating self-disorders to neurocognitive and psychopathological measures in first-episode schizophrenia.

Karl Erik Sandsten, Soren Wainio-Theberge, Julie Nordgaard, Troels Wesenberg Kjaer, Georg Northoff, Josef Parnas

Open access · hybridAbstract read
In one paragraph

Article in Early intervention in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
90.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Anomalous self-experiences in biotypes of psychosis.European archives of psychiatry and clinical neuroscience · 2026
    Article
  3. Article
  4. Article
  5. The Neurobiology of Formal Thought Disorder.Current topics in medicinal chemistry · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Karl Erik SandstenDepartment of Neuroscience, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-6274-4502
Soren Wainio-ThebergeUniversity of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada.
Julie NordgaardMental Health Center Amager, University Hospital of Copenhagen, Copenhagen, Denmark.
Troels Wesenberg KjaerDepartment of Neurology, University Hospital Zealand, Roskilde, Denmark.
Georg NorthoffUniversity of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada.
Josef ParnasMental Health Center Glostrup, University Hospital of Copenhagen, Copenhagen, Denmark.
University of Ottawa · CAAmager Hospital · DKGlostrup Hospital · DKUniversity of Copenhagen · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe notion of a disturbed self as the core feature of schizophrenia dates back to the founding texts on the illness. Since the development of the psychometric tool for examination of anomalous self-experience (EASE), self-disorders have become accessible to empirical research. Empirical studies have shown that EASE measured self-disorders predict schizophrenia spectrum in prospective studies and consistently show a selective hyper aggregation of self-disorder in schizophrenia and schizotypal disorders. The aim of this study is to investigate the relationship between self-disorders cognitive deficits and symptoms in schizophrenia.

methodsThirty-five non-acute first-episode patients with schizophrenia and 35 matched healthy controls were evaluated with EASE, cognitive deficits, and symptoms (PANSS positive, negative and general). [Correction added on 28 January 2022, after first online publication: the words, 'evaluated with' were missing and have now been added to the preceding sentence.]

resultsThe results show that self-disorders and symptoms are correlated among patients with schizophrenia, but not with cognitive deficits. Moreover, with the exception of attentional deficits, neurocognitive impairment was not significantly higher among patients with schizophrenia compared to healthy controls.

conclusionsWe argue that this adds support to a view of schizophrenia as being characterized by specific traits of pre-reflective self-disturbance, which are related to the severity of symptoms, whereas neurocognitive impairment reflects a separate or distinct aspect of schizophrenia.

Indexed as

Cognition DisordersSchizophreniaSchizotypal Personality DisorderHumansNeuropsychological TestsProspective StudiesSchizophrenic Psychologycognitionneuropsychologypsychopathologyschizophreniaself-disorder

Identifiers

PMID35081668
PMCPMC9786869
OpenAlexW4210803016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.