ArticleImmunity2022
Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5
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Article in Immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48citing papers in PubMed
–field-weighted citation impact
What it found
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Who cites it
48 citing papers in PubMed.
- Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026Review
- Regulation of follicular helper T cell subset differentiation in health and disease.Journal of molecular medicine (Berlin, Germany) · 2026Review
- Apoptotic Quality Control of Cellular Competence Limits Cryptic Germinal Center B Cell States.bioRxiv : the preprint server for biology · 2026Article
- eIF3e-mediated translational checkpoint maintains immune tolerance and prevents lymphoid malignancy.The Journal of experimental medicine · 2026Article
- Expression and Role of the RNA-Binding Protein, ZFP36L1, in Mouse T Follicular Helper Cell Differentiation and Function.European journal of immunology · 2026Article
- A unified network systems approach uncovers a core program underlying T follicular helper cell differentiation.Nature communications · 2026Article
- Modeling development of tertiary lymphoid structures in pulmonary tuberculosis by 3D profiling and trajectory analysis.bioRxiv : the preprint server for biology · 2026Article
- Siglec-G on B cells restrains the germinal center response by controlling T cell help during positive selection.bioRxiv : the preprint server for biology · 2026Article
- IL-1β and IL-6 synergistically drive murine TFH cell differentiation and maintenance in vitro.Immunology and cell biology · 2026Article
- Bioengineered anti-EpCAM-guided exosome nanocarriers delivering Foxp3 agonist butyrate achieve tissue-specific immunomodulation in autoimmune Sjögren's syndrome.Journal of nanobiotechnology · 2026Article
- IL-2 silencing enables Tfh cell expansion during vaccination but is redundant for antibody production.Immunology and cell biology · 2026Article
- Small particles of Echinococcus granulosus (spegs) and Echinococcus multilocularis (spems) promote follicular T helper cell expansion and are associated with IgE and IgG4 class switching in human lymph nodes.Parasites & vectors · 2026Article
- Immunodominance is a poor predictor of vaccine-induced T follicular helper cell quality.EBioMedicine · 2026Article
- Mechanistic roles and clinical applications of tertiary lymphoid structures in colorectal cancer drug resistance.Cancer drug resistance (Alhambra, Calif.) · 2026Review
- Multimodal analysis definesbioRxiv : the preprint server for biology · 2025Article
- Article
- Lymphoid B cells upregulate HIV-1 ex vivo and are linked to its expression in vivo.PLoS pathogens · 2025Article
- Germinal center formation is resilient to CD69 deletion on T follicular helper cells.Immunology and cell biology · 2025Article
- Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity.Nature immunology · 2025Article
- Beyond T-cell subsets: stemness and adaptation redefining immunity and immunotherapy.Cellular & molecular immunology · 2025Review
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Authors and funding
5 authors.
Chen-Hao YehDepartment of Immunology, Duke University School of Medicine, Durham, NC 27710, USA.
Joel FinneyDepartment of Immunology, Duke University School of Medicine, Durham, NC 27710, USA.
Takaharu OkadaLaboratory for Tissue Dynamics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa 230-0045, Japan.
Tomohiro KurosakiLaboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan.
Garnett KelsoeDepartment of Immunology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Surgery and Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: ghkelsoe@duke.edu.
Funding
Virus biology scientific research support componentUM1AI100645 · NIAID · DUKE UNIVERSITY · PI HAYNES, BARTON F. · 2012 to 2018
$204.7MNonhuman primate studies for development of a prototype HIV vaccine that induces broadly neutralizing antibodiesUM1AI144371 · NIAID · DUKE UNIVERSITY · PI HAYNES, BARTON F. · 2019 to 2025
$190.4MVirus and Antibody Gene Sequencing CoreP01AI131251 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Kevin Wiehe · 2017 to 2026
$40.7MVirology CoreP01AI089618 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI Jiwon Lee · 2011 to 2026
$40.0MStructures and Interactions of Antibodies Produced by Affinity MaturationU19AI117892 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HARRISON, STEPHEN COPLAN · 2015 to 2019
$9.2MNIAID NIH HHS P01 AI089618NIAID NIH HHS P01 AI131251NIAID NIH HHS U19 AI117892NIAID NIH HHS UM1 AI100645NIAID NIH HHS UM1 AI144371
Abstract
T follicular helper (Tfh) cells are defined by a Bcl6
Indexed as
AnimalsB-LymphocytesCell CommunicationCell DifferentiationCell ProliferationDendritic CellsGene Expression ProfilingGerminal CenterHistocompatibility Antigens Class IIMiceProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-CellReceptors, CXCR5Sphingosine-1-Phosphate ReceptorsT Follicular Helper CellsThy-1 AntigensCXCR5 protein, mouseHistocompatibility Antigens Class IIPdcd1 protein, mouseProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-CellReceptors, CXCR5sphingosine-1-phosphate receptor-2, mouseSphingosine-1-Phosphate ReceptorsThy-1 Antigensaffinity maturationgerminal centershumoral immunityS1pr2T:B interactionTfh cells
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.