Evidence map›Paper›PMID 35081320›Full record

ArticleAmerican journal of physiology. Cell physiology2022

Functional role of histamine receptors in the renal cortical collecting duct cells.

Anastasia V Sudarikova, Mikhail V Fomin, Regina F Sultanova, Ying Zhao, Samantha Perez, Mark Domondon, Margarita Shamatova, Daria V Lysikova, Denisha R Spires, Daria V Ilatovskaya

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Histamine regulates the activity and the expression of the NaInflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  2. Epithelial NaComprehensive Physiology · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Anastasia V SudarikovaDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.ORCID 0000-0003-0137-471X
Mikhail V FominDepartment of Physiology, Augusta University, Augusta, Georgia.
Regina F SultanovaDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Ying ZhaoDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Samantha PerezDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Mark DomondonDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Margarita ShamatovaInstitute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.
Daria V LysikovaInstitute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.
Denisha R SpiresDepartment of Physiology, Augusta University, Augusta, Georgia.ORCID 0000-0003-0722-2717
Daria V IlatovskayaDepartment of Physiology, Augusta University, Augusta, Georgia.ORCID 0000-0003-4832-4170
Augusta University · USMedical University of South Carolina · US

Funding

Mitochondria-Mediated Effects and Therapeutic Potential of Atrial Natriuretic Peptide in Salt-Sensitive Hypertension Diversity SupplementR01HL148114 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ILATOVSKAYA, DARIA · 2020 to 2024
$2.8M
NHLBI NIH HHS R01 HL148114
6 · The paper itself

Abstract

Histamine is an important immunomodulator, as well as a regulator of allergic inflammation, gastric acid secretion, and neurotransmission. Although substantial histamine level has been reported in the kidney, renal pathological and physiological effects of this compound have not been clearly defined. The goal of this study was to provide insight into the role of histamine-related pathways in the kidney, with emphasis on the collecting duct (CD), a distal part of the nephron important for the regulation of blood pressure. We report that all four histamine receptors (HRs) as well as enzymes responsible for histamine metabolism and synthesis are expressed in cultured mouse mpkCCD

Indexed as

Epithelial Sodium ChannelsKidney Tubules, CollectingAnimalsMiceNephronsReceptors, HistamineSodiumEpithelial Sodium ChannelsReceptors, HistamineSodiumcollecting ductepithelial Na+ channelshistaminehistamine receptorskidney

Identifiers

PMID35081320
PMCPMC8993525
OpenAlexW4210775606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.