Evidence map›Paper›PMID 35081238›Full record

ArticleRevista Brasileira de terapia intensiva

Extracorporeal membrane oxygenation for respiratory failure in children: the years before and after the 2009 H1N1 pandemic.

Felipe Rezende Caino de Oliveira, Orlei Ribeiro de Araujo, Daniel Garros, José Colleti Junior, Werther Brunow de Carvalho, Laurance Lequier

Open access · hybridAbstract read
In one paragraph

Article in Revista Brasileira de terapia intensiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Felipe Rezende Caino de OliveiraUnidade de Terapia Intensiva Pediátrica, Hospital Santa Catarina, São Paulo, São Paulo (SP), Brasil.ORCID 0000-0003-2729-0602
Orlei Ribeiro de AraujoUnidade de Terapia Intensiva Pediátrica, Grupo de Apoio ao Adolescente e à Criança com Câncer, Instituto de Oncologia Pediátrica, Universidade Federal de São Paulo - São Paulo (SP), Brasil.ORCID 0000-0001-8230-6801
Daniel GarrosUnidade de Terapia Intensiva Pediátrica, Stollery Children's Hospital - Edmonton, Alberta, Canadá.
José Colleti JuniorUnidade de Terapia Intensiva Pediátrica, Hospital Santa Catarina, São Paulo, São Paulo (SP), Brasil.ORCID 0000-0001-6734-5765
Werther Brunow de CarvalhoUnidade de Terapia Intensiva Pediátrica, Hospital Santa Catarina, São Paulo, São Paulo (SP), Brasil.ORCID 0000-0002-9164-616X
Laurance LequierUnidade de Terapia Intensiva Pediátrica, Stollery Children's Hospital - Edmonton, Alberta, Canadá.
Hospital São Paulo · BRStollery Children's Hospital · CASupport group for adolescents and children with cancer · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate whether there was any impact on the number of pediatric extracorporeal membrane oxygenation runs and survival rates in the years subsequent to the 2009 pandemic.

methodsWe studied two different periods of extracorporeal membrane oxygenation support for respiratory failure in children by analyzing datasets from the Extracorporeal Life Support Organization. Autoregressive integrated moving average models were constructed to estimate the effect of the pandemic. The year 2009 was the year of intervention (the H1N1 epidemic) in an interrupted time series model. Data collected from 2001 - 2010 were considered preintervention, and data collected from 2010 - 2017 were considered postintervention.

resultsThere was an increase in survival rates in the period 2010 - 2017 compared to 2001 - 2010 (p < 0.0001), with a significant improvement in survival when extracorporeal membrane oxygenation was performed for acute respiratory failure due to viral pneumonia. The autoregressive integrated moving average model shows an increase of 23 extracorporeal membrane oxygenation runs per year, prior to the point of the level effect (2009). In terms of survival, the preslope shows that there was no significant increase in survival rates before 2009 (p = 0.41), but the level effect was nearly significant after two years (p = 0.05), with a 6% increase in survival. In four years, there was an 8% (p = 0.03) increase in survival, and six years after 2009, there was up to a 10% (p = 0.026) increase in survival.

conclusionIn the years following 2009, there was a significant, global incremental increase in the extracorporeal membrane oxygenation survival rates for all runs, mainly due to improvements in the technology and treatment protocols for acute respiratory failure related to viral pneumonia and other respiratory conditions.

Indexed as

Extracorporeal Membrane OxygenationInfluenza A Virus, H1N1 SubtypeRespiratory Distress SyndromeRespiratory InsufficiencyChildHumansPandemicsRetrospective Studies

Identifiers

PMID35081238
PMCPMC8889597
OpenAlexW4210653309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.