Trial reportPloS one2022
Environmental effect of air versus gas tamponade in the management of rhegmatogenous retinal detachment VR surgery: A multicentre study of 3,239 patients.
Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- [Sulphur hexafluoride (SFDie Ophthalmologie · 2026Review
- Sustainability in vitreoretinal surgery: environmental impact and carbon emission reduction strategies.International ophthalmology · 2026Review
- Contribution of hospitals and clinical services to global warming: a scoping systematic review.Frontiers in public health · 2026Article
- Sustainability practices made easy.Eye (London, England) · 2025Review
- Effectiveness of Interventions to Reduce Carbon-Emissions Within Secondary Healthcare: Systematic Review and Evidence and Gap Map.Campbell systematic reviews · 2025Review
- An Innovative Strategy for Sustainability Assurance in Orthopedic Surgery.Medical sciences (Basel, Switzerland) · 2025Article
- Sustainable practices in ophthalmology-steps towards environmental stewardship in healthcare.Wiener medizinische Wochenschrift (1946) · 2025Review
- From Innovation to Conservation: Sustainable Pathways in Vitreoretinal Practice.Journal of ophthalmology · 2025Review
- Intraocular gases and climate change: a call for sustainable vitreoretinal surgery.Frontiers in public health · 2025Article
- Advancing Sustainability in Ophthalmic Surgeries and Interventions: A Narrative Review of Environmental Impact and Best Practices.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Contributions of Medical Greenhouse Gases to Climate Change and Their Possible Alternatives.International journal of environmental research and public health · 2024Review
- Thirteen year experience of vitrectomy and air tamponade for primary retinal detachment repair with clinical outcomes.Scientific reports · 2024Article
- Retinal detachment.Nature reviews. Disease primers · 2024Review
- Reducing the use of fluorinated gases in vitreoretinal surgery.Eye (London, England) · 2024Article
- [Survey and reduction of waste production from eye surgery].Die Ophthalmologie · 2023Article
- Clinical characteristics of primary pars plana vitrectomy combined with air filling for rhegmatogenous retinal detachment.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report the potential reduction of carbon emissions by utilising air-tamponade (AT), where possible, instead of fluorinated gases in the management of rhegmatogenous retinal detachment (RRD). We compared the carbon CO2 emissions produced at two large tertiary referral vitreoretinal (VR) centres where RRD are exclusively repaired using fluorinated gases to a tertiary VR mass of each gas used according to the Intergovernmental Panel on Climate Change. MATERIALS AND
methodsRetrospective, continuous, comparative multicentre study of all procedures using fluorinated gases between 01/01/17-31/12/20 at the Manchester Royal Eye Hospital (MREH) and Birmingham and Midland Eye Centre (BMEC), and between 01/01/19-31/12/2020 at the University Hospitals Coventry and Warwickshire (UHCW).
resultsWe report on 3,239 (SF6:1,415 [43.7%], C2F6:1,235 [38.1%], C3F8:541 [16.7%], Air:48 [1.5%]) procedures. UHCW and BMEC utilise single use 30ml and 75ml cannisters, respectively and MREH use multi-use gas cylinders. UHCW used AT in 48 (70%) of RRD repairs. Mean equivalent mass CO2/patient was MREH:115.9kg, BMEC:7.9kg and UHCW:1.9kg. If assuming all centres used 30ml cannisters, the mean equivalent mass CO2/patient was MREH:3.5 kg, BMEC:3.1kg and UHCW:1.9kg. AT enabled UHCW to greatly reduce the need for the most environmentally damaging SF6 gas, leading to lower CO2 emissions by 47.0% and 41.1% compared to MREH and BMEC, respectively.
conclusionWe demonstrate how AT vs. the fluorinated gases can reduce in carbon footprint in the management of RRD. Further studies are required to determine the most 'environment-friendly' intraocular tamponade without compromising patient outcomes centre that also routinely employs AT in selected RRD cases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.