ArticleScience advances2022
A programmable and skin temperature-activated electromechanical synergistic dressing for effective wound healing.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 123 citations in OpenAlex.
- Engineering Injectable Co-Assembled Hyaluronic Acid-Based Hydrogel by Photothermal Driven Recombinant Human Type III Collagen-Stabilized MoSSmall (Weinheim an der Bergstrasse, Germany) · 2026Article
- Multi-Axis Stretchable Zippers for Personalized Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A multifunctional porous interface bridging 3D architected electronics with skin.Science advances · 2026Article
- Seta-Inspired Mechano-Intelligent Janus Bandage with Coordinated Adhesion-Contraction for Minimizing Scarring.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Modifiable PEDOT:PSS-based flexible diagnostic and therapeutic dressings for personalized wound management.Microsystems & nanoengineering · 2026Article
- Spatial-chromatic encoding cosmetic contact lenses for enhanced natural eye tracking.Nature communications · 2026Article
- Materials and System Design for Self-Decision Bioelectronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Electric-based dressing for wound management.Frontiers in cellular and infection microbiology · 2026Review
- A bioabsorbable body-coupling-electrotherapy suture.Nature communications · 2025Article
- Biomimetic electric interface-mediated cellular activation promotes diabetic wound healing via self-powered wearable thermoelectric patch.Materials today. Bio · 2025Article
- Mining extreme properties from a large metamaterial database.Nature communications · 2025Article
- Electrical Stimulation Therapy - Dedicated to the Perfect Plastic Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Smartphone administered pulsed radio frequency energy therapy for expedited cutaneous wound healing.NPJ digital medicine · 2025Article
- A strain-programmed lignin-based Janus patch for rapid healing of postoperative rectal wounds.Theranostics · 2025Article
- Chronic wound management: a liquid diode-based smart bandage with ultrasensitive pH sensing ability.Microsystems & nanoengineering · 2024Article
- Unleashing the Potential of Electroactive Hybrid Biomaterials and Self-Powered Systems for Bone Therapeutics.Nano-micro letters · 2024Review
- Core-Shell Gel Nanofiber Scaffolds Constructed by Microfluidic Spinning toward Wound Repair and Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Antibacterial and Antibiofilm Properties of Native Australian Plant Endophytes against Wound-Infecting Bacteria.Microorganisms · 2024Article
- Wound management materials and technologies from bench to bedside and beyond.Nature reviews. Materials · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanical regulation and electric stimulation hold great promise in skin tissue engineering for manipulating wound healing. However, the complexity of equipment operation and stimulation implementation remains an ongoing challenge in clinical applications. Here, we propose a programmable and skin temperature-activated electromechanical synergistic wound dressing composed of a shape memory alloy-based mechanical metamaterial for wound contraction and an antibacterial electret thin film for electric field generation. This strategy is successfully demonstrated on rats to achieve effective wound healing in as short as 4 and 8 days for linear and circular wounds, respectively, with a statistically significant over 50% improvement in wound closure rate versus the blank control group. The optimally designed electromechanical synergistic stimulation could regulate the wound microenvironment to accelerate healing metabolism, promote wound closure, and inhibit infection. This work provided an effective wound healing strategy in the context of a programmable temperature-responsive, battery-free electromechanical synergistic biomedical device.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.