Evidence map›Paper›PMID 35080878›Full record

ArticleBiomacromolecules2022

Ice Recrystallization Inhibition Is Insufficient to Explain Cryopreservation Abilities of Antifreeze Proteins.

Yuling Sun, Daria Maltseva, Jie Liu, Theordore Hooker, Volker Mailänder, Hans Ramløv, Arthur L DeVries, Mischa Bonn, Konrad Meister

Open access · hybridAbstract read
In one paragraph

Article in Biomacromolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Synthetic Antifreeze Glycoproteins with Potent Ice-Binding Activity.Chemistry of materials : a publication of the American Chemical Society · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Yuling SunMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0001-8582-5244
Daria MaltsevaMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Jie LiuInstitute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
Theordore HookerUniversity of Alaska Southeast, Juneau, Alaska 99801, United States.
Volker MailänderMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Hans RamløvRoskilde University, 4000 Roskilde, Denmark.ORCID 0000-0003-1113-0583
Arthur L DeVriesUniversity of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Mischa BonnMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0001-6851-8453
Konrad MeisterMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0002-6853-6325
Max Planck Institute for Polymer Research · DEChinese Academy of Sciences · CNJohannes Gutenberg University Mainz · DERoskilde University · DKUniversity of Alaska Southeast · USUniversity of Illinois Urbana-Champaign · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
Biomedical Learning and Student Training (BLaST) ProgramUL1GM118991 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI HUEFFER, KARSTEN · 2015 to 2023
$19.0M
Biomedical Learning and Student Training (BLaST) ProgramRL5GM118990 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI HUEFFER, KARSTEN, REYNOLDS, ARLEIGH JAMES · 2015 to 2023
$10.5M
Biomedical Learning and Student Training (BLaST) ProgramTL4GM118992 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI HUEFFER, KARSTEN, REYNOLDS, ARLEIGH JAMES · 2015 to 2023
$7.1M
NIGMS NIH HHS P20 GM103395NIGMS NIH HHS RL5 GM118990NIGMS NIH HHS TL4 GM118992NIGMS NIH HHS UL1 GM118991
6 · The paper itself

Abstract

Antifreeze proteins (AFPs) and glycoproteins (AFGPs) are exemplary at modifying ice crystal growth and at inhibiting ice recrystallization (IRI) in frozen solutions. These properties make them highly attractive for cold storage and cryopreservation applications of biological tissue, food, and other water-based materials. The specific requirements for optimal cryostorage remain unknown, but high IRI activity has been proposed to be crucial. Here, we show that high IRI activity alone is insufficient to explain the beneficial effects of AF(

Indexed as

Antifreeze ProteinsIceCryopreservationCryoprotective AgentsFreezingHumansAntifreeze ProteinsCryoprotective AgentsIce

Identifiers

PMID35080878
PMCPMC8924859
OpenAlexW4210717389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.