Evidence map›Paper›PMID 35080739›Full record

ReviewCurrent oncology reports2022

Optimal Use of Tumor-Based Molecular Assays for Localized Prostate Cancer.

Soum D Lokeshwar, Jamil S Syed, Daniel Segal, Syed N Rahman, Preston C Sprenkle

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Soum D LokeshwarDepartment of Urology, Yale University School of Medicine, 800 Howard Ave, New Haven, CT, 06510, USA.
Jamil S SyedDepartment of Urology, Yale University School of Medicine, 800 Howard Ave, New Haven, CT, 06510, USA.
Daniel SegalDepartment of Urology, Yale University School of Medicine, 800 Howard Ave, New Haven, CT, 06510, USA.
Syed N RahmanDepartment of Urology, Yale University School of Medicine, 800 Howard Ave, New Haven, CT, 06510, USA.
Preston C SprenkleDepartment of Urology, Yale University School of Medicine, 800 Howard Ave, New Haven, CT, 06510, USA. Preston.Sprenkle@yale.edu.ORCID 0000-0003-0502-9294

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Dietmar J Kappes · 1985 to 2026
$138.8M
TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221704 · NCI · HUNTER COLLEGE · PI Ming-Chin Yeh · 2018 to 2026
$10.6M
NCI NIH HHS P30 CA006927NCI NIH HHS U54 CA221704
6 · The paper itself

Abstract

purposeof reviewThe use of genomic testing for prostate cancer continues to grow; however, utilization remains institutionally dependent. Herein, we review current tissue-based markers and comment on current use with active surveillance and prostate MRI. RECENT

findingsWhile data continues to emerge, several studies have shown a role for genomic testing for treatment selection. Novel testing options include ConfirmMDx, ProMark, Prolaris, and Decipher, which have shown utility in select patients. The current body of literature on this specific topic remains very limited; prospective trials with long-term follow-up are needed to improve our understanding on how these genomic tests fit when combined with our current clinical tools. As the literature matures, it is likely that newer risk calculators that combine our classic clinical variables with genomic and imaging data will be developed to bring about standard protocols for prostate cancer decision-making.

Indexed as

Prostatic NeoplasmsGenomicsHumansMagnetic Resonance ImagingMalePrognosisProspective StudiesActive surveillanceBiomarkersDecipherGenomicsmpMRIProstate cancer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.