Evidence map›Paper›PMID 35080501›Full record

ArticleJournal of medical Internet research2022

A Novel Virtual Reality Assessment of Functional Cognition: Validation Study.

Lilla Alexandra Porffy, Mitul A Mehta, Joel Patchitt, Celia Boussebaa, Jack Brett, Teresa D'Oliveira, Elias Mouchlianitis, Sukhi S Shergill

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  8. Impact of Virtual Reality Cognitive and Motor Exercises on Brain Health.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Lilla Alexandra PorffyInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0001-7420-3618
Mitul A MehtaInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-1152-5323
Joel PatchittInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-4662-739X
Celia BoussebaaInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-3214-8117
Jack BrettFaculty of Media and Communications, Bournemouth University, Bournemouth, United Kingdom.ORCID 0000-0003-1226-3089
Teresa D'OliveiraInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-3126-823X
Elias Mouchlianitis *School of Psychology, University of East London, London, United Kingdom.ORCID 0000-0003-0329-5492
Sukhi S Shergill *Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-4928-9100
King's College London · GBBournemouth University · GBBrighton and Sussex Medical School · GBMedway School of Pharmacy · GBUniversity of East London · GB

Funding

Medical Research Council G0901868Medical Research Council MR/N013700/1
6 · The paper itself

Abstract

backgroundCognitive deficits are present in several neuropsychiatric disorders, including Alzheimer disease, schizophrenia, and depression. Assessments used to measure cognition in these disorders are time-consuming, burdensome, and have low ecological validity. To address these limitations, we developed a novel virtual reality shopping task-VStore.

objectiveThis study aims to establish the construct validity of VStore in relation to the established computerized cognitive battery, Cogstate, and explore its sensitivity to age-related cognitive decline.

methodsA total of 142 healthy volunteers aged 20-79 years participated in the study. The main VStore outcomes included verbal recall of 12 grocery items, time to collect items, time to select items on a self-checkout machine, time to make the payment, time to order coffee, and total completion time. Construct validity was examined through a series of backward elimination regression models to establish which Cogstate tasks, measuring attention, processing speed, verbal and visual learning, working memory, executive function, and paired associate learning, in addition to age and technological familiarity, best predicted VStore performance. In addition, 2 ridge regression and 2 logistic regression models supplemented with receiver operating characteristic curves were built, with VStore outcomes in the first model and Cogstate outcomes in the second model entered as predictors of age and age cohorts, respectively.

resultsOverall VStore performance, as indexed by the total time spent completing the task, was best explained by Cogstate tasks measuring attention, working memory, paired associate learning, and age and technological familiarity, accounting for 47% of the variance. In addition, with λ=5.16, the ridge regression model selected 5 parameters for VStore when predicting age (mean squared error 185.80, SE 19.34), and with λ=9.49 for Cogstate, the model selected all 8 tasks (mean squared error 226.80, SE 23.48). Finally, VStore was found to be highly sensitive (87%) and specific (91.7%) to age cohorts, with 94.6% of the area under the receiver operating characteristic curve.

conclusionsOur findings suggest that VStore is a promising assessment that engages standard cognitive domains and is sensitive to age-related cognitive decline.

Indexed as

Cognition DisordersSchizophreniaVirtual RealityCognitionHumansNeuropsychological Testscognitionfunctional capacityfunctional cognitionneuropsychological testingvirtual realityvirtual reality assessment

Identifiers

PMID35080501
PMCPMC8829700
OpenAlexW3201681256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.