Evidence map›Paper›PMID 35080450›Full record

ArticleJournal of clinical microbiology2022

Genomic Epidemiology Links Burkholderia pseudomallei from Individual Human Cases to B. pseudomallei from Targeted Environmental Sampling in Northern Australia.

Jessica R Webb, Mark Mayo, Audrey Rachlin, Celeste Woerle, Ella Meumann, Vanessa Rigas, Glenda Harrington, Mirjam Kaestli, Bart J Currie

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Burkholderia pseudomallei and melioidosis.Nature reviews. Microbiology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jessica R WebbGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.ORCID 0000-0002-6332-039X
Mark MayoGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Audrey RachlinGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Celeste WoerleGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Ella MeumannGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Vanessa RigasGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Glenda HarringtonGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Mirjam KaestliGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.
Bart J CurrieGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Northern Territory, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Each case of melioidosis results from a single event when a human is infected by the environmental bacterium Burkholderia pseudomallei. Darwin, in tropical northern Australia, has the highest incidences of melioidosis globally, and the Darwin Prospective Melioidosis Study (DPMS) commenced in 1989, documenting all culture-confirmed melioidosis cases. From 2000 to 2019, we sampled DPMS patients' environments for B. pseudomallei when a specific location was considered to be where infection occurred, with the aim of using genomic epidemiology to understand B. pseudomallei transmission and infecting scenarios. Environmental sampling was performed at 98 DPMS patient sites, where we collected 975 environmental samples (742 soil and 233 water). Genotyping matched the clinical and epidemiologically linked environmental B. pseudomallei for 19 patients (19%), with the environmental isolates cultured from soil (

Indexed as

Burkholderia pseudomalleiMelioidosisAustraliaGenomicsHumansProspective StudiesSoilWaterSoilWaterAustraliaBurkholderia pseudomalleiDarwinepidemiologygenomicsgenotypingmelioidosismolecular epidemiologyNorthern Territoryphylogeneticspoint sourcepublic health

Identifiers

PMID35080450
PMCPMC8925902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.