Evidence map›Paper›PMID 35080318›Full record

ReviewPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2022

Primary atopic disorders and chronic skin disease.

Bianca Laura Cinicola, Stefania Corrente, Riccardo Castagnoli, Vassilios Lougaris, Giuliana Giardino, Lucia Leonardi, Stefano Volpi, Francesco La Torre, Silvia Federici, Annarosa Soresina and 4 more

Open access · hybridAbstract readReview
In one paragraph

Review in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Italian pediatric experts' consensus statement on diagnosis and management of primary atopic disorders.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Guideline
  2. Review
  3. Review
  4. Update on the genetics of allergic diseases.The Journal of allergy and clinical immunology · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Primary atopic disorders and chronic skin disease.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Bianca Laura CinicolaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Stefania CorrenteDivision of Pediatrics, S. Camillo-Forlanini Hospital, Rome, Italy.
Riccardo CastagnoliPediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.ORCID 0000-0003-0029-9383
Vassilios LougarisDepartment of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia and ASST-Spedali Civili di Brescia, Brescia, Italy.ORCID 0000-0003-2303-9533
Giuliana GiardinoPediatric Section, Department of Translational Medical Sciences, Federico II University, Naples, Italy.ORCID 0000-0002-0621-9527
Lucia LeonardiDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-2554-1263
Stefano VolpiCenter for Autoinflammatory Diseases and Immunodeficiency, IRCCS Istituto Giannina Gaslini, Università degli Studi di Genova, Genoa, Italy.ORCID 0000-0002-7129-868X
Francesco La TorreDepartment of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.ORCID 0000-0002-5235-2900
Silvia FedericiDivision of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.ORCID 0000-0001-7780-6430
Annarosa SoresinaUnit of Pediatric Immunology, Pediatrics Clinic, University of Brescia, ASST-Spedali Civili Brescia, Brescia, Italy.
Caterina CancriniAcademic Department of Pediatrics (DPUO), Immune and Infectious Diseases Division, Research Unit of Primary Immunodeficiencies, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID 0000-0001-8410-9617
Gian Luigi MarsegliaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.ORCID 0000-0003-3662-0159
Fabio CardinaleDepartment of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.
Immunology Task Force of the Italian Society of Pediatric Allergy, Immunology (SIAIP)
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITOspedale Pediatrico Giovanni XXIII · ITSapienza University of Rome · ITUniversity of Pavia · ITBambino Gesù Children's Hospital · ITCarlo Forlanini Hospital · ITFederico II University Hospital · ITIstituto Giannina Gaslini · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary atopic disorders (PADs) are monogenic diseases characterized by allergy or atopy-related symptoms as fundamental features. In patients with PADs, primary immune deficiency and immune dysregulation symptoms are usually coexist. Chronic skin disease, manifesting with erythroderma, severe atopic dermatitis or eczema, and urticaria, is one of the main features observed in PADs, such as hyper-IgE syndromes, Omenn syndrome, Wiskott-Aldrich syndrome, IPEX-linked syndrome, skin barrier disorders, as well as some autoinflammatory diseases. The recognition of PADs in the context of an allergic phenotype is crucial to ensure prompt diagnosis and appropriate treatment. This article provides an overview of the main PADs with skin involvement.

Indexed as

EczemaHypersensitivity, ImmediateJob SyndromeSkin DiseasesUrticariaHumansallergyIgEinborn errors of immunityprimary atopic disordersskin

Identifiers

PMID35080318
PMCPMC9306837
OpenAlexW4210248755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.